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The Burden of Gout and Its Attributable Risk Factors in the Middle East and North Africa Region, 1990 to 2019 Publisher Pubmed



Amiri F1 ; Kolahi AA2 ; Nejadghaderi SA3 ; Noori M4 ; Khabbazi A5 ; Sullman MJM6 ; Kaufman JS7 ; Collins GS8 ; Safiri S9
Authors
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Authors Affiliations
  1. 1. Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, and Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  4. 4. School of Medicine, Iran University of Medical Sciences, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Connective Tissue Diseases Research Center, Department of Internal Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  6. 6. Department of Life and Health Sciences, Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
  7. 7. Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, QC, Canada
  8. 8. Centre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
  9. 9. Connective Tissue Diseases Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Journal of Rheumatology Published:2023


Abstract

Objective. This study reported the burden of gout and its attributable risk factors in the Middle East and North Africa (MENA) region between 1990 and 2019 by age, sex, and sociodemographic index (SDI). Methods. Data on the prevalence, incidence, and years lived with disability (YLD) due to gout were obtained from the Global Burden of Disease 2019 study for the 21 countries in the MENA region, from 1990 to 2019. Results. In 2019, the regional age-standardized point prevalence and annual incidence rates of gout were 509.1 and 97.7 per 100,000 population, which represent a 12% and 11.1% increase since 1990, respectively. Moreover, in 2019 the regional age-standardized YLD rate was 15.8 per 100,000 population, an 11.7% increase since 1990. In 2019, Qatar and Afghanistan had the highest and lowest age-standardized YLD rates, respectively. Regionally, the age-standardized point prevalence of gout increased with age up to the oldest age group, and it was more prevalent among males in all age groups. In addition, there was an overall positive association between SDI and the burden of gout between 1990 and 2019. In 2019, high BMI (46.1%) was the largest contributor to the burden of gout in the MENA region. Conclusion. There were large intercountry variations in the burden of gout, but in general, it has increased in MENA over the last 3 decades. This increase is in line with the global trends of gout. However, the age-standardized YLD rate change was higher in MENA than at the global level. © 2023 The Journal of Rheumatology.
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