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The Effects of Pomegranate Consumption on Obesity Indices in Adults: A Systematic Review and Meta-Analysis Publisher



Bahari H1, 2 ; Pourreza S3 ; Goudarzi K4 ; Mirmohammadali SN5 ; Asbaghi O6, 7 ; Kolbadi KSH8 ; Naderian M9, 10 ; Hosseini A9
Authors
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Authors Affiliations
  1. 1. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran
  3. 3. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Faculty of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran
  5. 5. Department of Food, Nutrition, Dietetics and Health, Kansas State University, Manhattan, KS, United States
  6. 6. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  7. 7. Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  8. 8. Faculty of Medicine, Iran University of Medical Science, Tehran, Iran
  9. 9. Department of Pharmacognosy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
  10. 10. Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran

Source: Food Science and Nutrition Published:2024


Abstract

Evidence supports the potential application of polyphenols as agents against obesity. Pomegranate is one of the fruits that possess a high content of polyphenols. This systematic review and meta-analysis of randomized controlled trials (RCTs) sought to evaluate the effects of pomegranate consumption on obesity indices, including body mass index (BMI), body weight, waist circumference (WC), fat mass (FM), body fat percentage (BFP), and fat-free mass (FFM) in adults. Relevant RCTs were obtained by searching databases, including PubMed, SCOPUS, and Web of Science, up to May 2023. Heterogeneity tests of the included trials were performed using the I2 statistic. Random effects models were assessed based on the heterogeneity tests, and pooled data were determined as the weighted mean difference with a 95% confidence interval. Pooled analysis of 28 trials revealed that pomegranate consumption led to a significant reduction in body weight (WMD: −1.97, 95% CI: −2.91, −1.03, p <.05), and a significant decrease in BMI (WMD: −0.48, 95% CI: −0.76, −0.20, p <.05) in comparison with the control group. However, there were no significant effects on WC, FM, FFM, and BFP in comparison with the control group. Pomegranate consumption may yield a beneficial effect on body weight and BMI in adults. However, there were no significant effects on WC, FM, FFM, and BFP, by pomegranate consumption. Also, pomegranate consumption can reduce body weight, BMI, WC, and BFP in obese adults. Long-term trials with different doses of pomegranate are needed. © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
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