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Nanozymes With Intrinsic Peroxidase-Like Activities Publisher



Attar F1 ; Shahpar MG2 ; Rasti B3 ; Sharifi M4 ; Saboury AA5 ; Rezayat SM6 ; Falahati M4
Authors
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Authors Affiliations
  1. 1. Department of Biology, Faculty of Food Industry & Agriculture, Standard Research Institute (SRI), Karaj, Iran
  2. 2. Department of Cellular and Molecular Biology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  3. 3. Department of Microbiology, Faculty of Basic Sciences, Lahijan Branch, Islamic Azad University (IAU), Lahijan, Guilan, Iran
  4. 4. Department of Nanotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
  5. 5. Department of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran
  6. 6. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Molecular Liquids Published:2019


Abstract

Over the past few decades, studies have focused on nanomaterials with enzyme-like features (nanozymes) as simple, stable, high-performance alternatives to natural enzymes in a wide range of implementations. A variety of inorganic nanomaterials including Cd, carbon based nanomaterials, CeO 2 , Co 3 O 4 , CuO, Au, Fe, Mn, Pd, Pt, SiO 2 , Ag, VO 2 , and Zn NPs have been considerably used to mimic the activity of naturally occurring enzymes. These nanomaterials have shown to mimic extensively enzyme-like activities, and great progresses have been made in these systems due to the enormous development in nano-research and the distinctive properties of nanomaterials. To accentuate the growth in the field of nanozymes, this review considers different inorganic nanomaterials that have been investigated to mimic peroxidase-like enzyme in biological, chemical and medical applications. We discuss regarding the kinetics, mechanisms and applications of peroxidase-like nanozymes. Finally, we will discuss regarding the different parameters that influence the catalytic activity of nanozymes and focus on the current challenges and future outcomes. © 2018 Elsevier B.V.
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