Drug-Drug Interaction Between Psychiatric Medications and Experimental Treatments Forcoronavirusdisease-19:A Mini-Review Publisher



Baradaran H¹ ; Gorgzadeh N¹ ; Seraj H² ; Asadi A² ; Shamshirian D³ ; Rezapour M⁴
Source: Open Access Macedonian Journal of Medical Sciences Published:2020

Abstract

The pandemic of coronavirus disease (COVID)-2019 has been affected many people all around the world. Patients with mental disorders are not as safe as others; also, they might be more vulnerable in such situations. These patients take various medications, which can lead to numerous drug-drug interactions with experimental drugs uses against COVID-19. According to the potential critical interactions, we reviewed the reputable databases to find the interactions between main categories of psychiatric medications (e.g., antidepressants, anti-psychotics, sedative/hypnotics, and mood stabilizers) when used in concomitant with COVID-19 experimental agents (e.g., hydroxychloroquine, lopinavir/ritonavir, atazanavir, and chloroquine). We hope the list provided in this review helps the clinical care staff in treating patients with mental illness infected with severe acute respiratory syndrome coronavirus 2 during the COVID-19 pandemic. © 2020 Hananeh Baradaran, Nazanin Gorgzadeh, Houman Seraj, Anahita Asadi, Danial Shamshirian, Maryam Rezapour.