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Pharmacological Treatments of Covid-19 Publisher Pubmed



Sahebnasagh A1 ; Avan R2 ; Saghafi F3 ; Mojtahedzadeh M4 ; Sadremomtaz A5 ; Arasteh O6 ; Tanzifi A7, 8 ; Faramarzi F9 ; Negarandeh R10 ; Safdari M11 ; Khataminia M12 ; Rezai Ghaleno H13 ; Habtemariam S14 ; Khoshi A15
Authors
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Authors Affiliations
  1. 1. Clinical Research Center, Department of Internal Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
  2. 2. Department of Clinical Pharmacy, Medical Toxicology and Drug Abuse Research Center (MTDRC), Faculty of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
  3. 3. Department of Clinical Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  4. 4. Department of Clinical Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. XB20 Drug Design, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, 9700 AD, Netherlands
  6. 6. Department of Clinical Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Sepanta Faragene Azma Research Laboratory. Co. LTD., Gorgan, Iran
  8. 8. Department of Parasitology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  9. 9. Clinical Pharmacy Research Center, Iran University of Medical Sciences, Tehran, Iran
  10. 10. Student Research Committee, Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
  11. 11. Department of Orthopedic Surgery, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
  12. 12. Student Research Committee, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  13. 13. Department of Surgery, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
  14. 14. Pharmacognosy Research Laboratories and Herbal Analysis Services, University of Greenwich, Central Avenue, Chatham-Maritime, Kent, ME4 4TB, United Kingdom
  15. 15. Department of Clinical Biochemistry, School of Medicine, North Khorasan University of Medical Sciences, Arkan roadway, Bojnurd, Iran

Source: Pharmacological Reports Published:2020


Abstract

The viral infection due to the new coronavirus or coronavirus disease 2019 (COVID-19), which was reported for the first time in December 2019, was named by the World Health Organization (WHO) as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV2), because of the very similar genome and also its related symptoms to SARS-CoV1. The ongoing COVID-19 pandemic with significant mortality, morbidity, and socioeconomic impact is considered by the WHO as a global public health emergency. Since there is no specific treatment available for SARS-CoV2 infection, and or COVID-19, several clinical and sub-clinical studies are currently undertaken to find a gold-standard therapeutic regimen with high efficacy and low side effect. Based on the published scientific evidence published to date, we summarized herein the effects of different potential therapies and up-to-date clinical trials. The review is intended to help readers aware of potentially effective COVID-19 treatment and provide useful references for future studies. © 2020, Maj Institute of Pharmacology Polish Academy of Sciences.
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