Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin

Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin Publisher Pubmed

Mehrani Y^{1, 2} ; Morovati S³ ; Tajik T⁴ ; Sarmadi S⁵ ; Bitaraf A⁶ ; Sourani Z⁷ ; Shahverdi M^{7, 8} ; Javadi H⁹ ; Kakish JE¹ ; Bridle BW¹ ; Karimi K¹

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1. Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, N1G 2W1, ON, Canada
2. Department of Clinical Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, 91779-48974, Iran
3. Division of Biotechnology, Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, 71557-13876, Iran
4. Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, 91779-48974, Iran
5. Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, 14199-63114, Iran
6. Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, 14167-53955, Iran
7. Department of Pathology, School of Veterinary Medicine, Shahrekord University, Shahrekord, 88186-34141, Iran
8. Clinical Biochemistry Research Center, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, 88157-13471, Iran
9. Department of Medical Sciences, Schulich School of Medicine & Dentistry, University of Western Ontario, London, N6A 3K7, ON, Canada

Source: Cells Published:2024

Abstract

The skin is a dynamic organ with a complex immune network critical for maintaining balance and defending against various pathogens. Different types of cells in the skin, such as mast cells (MCs) and group 2 innate lymphoid cells (ILC2s), contribute to immune regulation and play essential roles in the early immune response to various triggers, including allergens. It is beneficial to dissect cell-to-cell interactions in the skin to elucidate the mechanisms underlying skin immunity. The current manuscript concentrates explicitly on the communication pathways between MCs and ILC2s in the skin, highlighting their ability to regulate immune responses, inflammation, and tissue repair. Furthermore, it discusses how the interactions between MCs and ILC2s play a crucial role in various skin conditions, such as autoimmune diseases, dermatological disorders, and allergic reactions. Understanding the complex interactions between MCs and ILC2s in different skin conditions is crucial to developing targeted treatments for related disorders. The discovery of shared pathways could pave the way for novel therapeutic interventions to restore immunological balance in diseased skin tissues. © 2024 by the authors.

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Nima Rezaei (6)

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Style	Citing Format
MLA	Mehrani Y, et al.. "Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin." Cells, vol. 13, no. 5, 2024, pp. -.
APA	Mehrani Y, Morovati S, Tajik T, Sarmadi S, Bitaraf A, Sourani Z, Shahverdi M, Javadi H, Kakish JE, Bridle BW, Karimi K (2024). Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin. Cells, 13(5), -.
Chicago	Mehrani Y, Morovati S, Tajik T, Sarmadi S, Bitaraf A, Sourani Z, Shahverdi M, et al.. "Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin." Cells 13, no. 5 (2024): -.
Harvard	Mehrani Y et al. (2024) 'Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin', Cells, 13(5), pp. -.
Vancouver	Mehrani Y, Morovati S, Tajik T, Sarmadi S, Bitaraf A, Sourani Z, et al.. Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin. Cells. 2024;13(5):-.
BibTex	@article{ author = {Mehrani Y and Morovati S and Tajik T and Sarmadi S and Bitaraf A and Sourani Z and Shahverdi M and Javadi H and Kakish JE and Bridle BW and Karimi K}, title = {Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin}, journal = {Cells}, volume = {13}, number = {5}, pages = {-}, year = {2024} }
RIS	TY - JOUR AU - Mehrani Y AU - Morovati S AU - Tajik T AU - Sarmadi S AU - Bitaraf A AU - Sourani Z AU - Shahverdi M AU - Javadi H AU - Kakish JE AU - Bridle BW AU - Karimi K TI - Communication Between Mast Cells and Group 2 Innate Lymphoid Cells in the Skin JO - Cells VL - 13 IS - 5 SP - EP - PY - 2024 ER -

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