Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology

Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology Publisher Pubmed

Rey D¹ ; Amirzargar A² ; Areces C¹ ; Enriquezdesalamanca M¹ ; Marco J¹ ; Abdelfatahkhalil S³ ; Fernandezhonrado M³ ; Muniz E¹ ; Martinvilla JM¹ ; Arnaizvillena A¹

Show Affiliations

1. Departamento de Inmunologia, Facultad de Medicina, Universidad Complutense, Pabellon 5, Madrid, 28040, Spain
2. Molecular Immunology Research Center, Medical School, Tehran University of Medical Sciences, Tehran, Iran
3. Departament of Haematology, Madrid Regional Blood Center, Madrid, Spain

Source: Immunological Investigations Published:2015

Abstract

HLA class I and II alleles have been studied in a population from Gorgan (North East Iranian city bordering Turkmenistan). This population is composed of mainly Turkmen who speak Oghuz Turkish language. Comparison of Gorgan people HLA profile has been carried out with about 7984 HLA chromosomes from other worldwide populations; extended haplotypes and three dimension genetic distances have been calculated by using neighbor-joining and correspondence relatedness analyses. Most frequent extended HLA haplotypes show a Siberian/Mediterranean admixture and closest populations are Chuvashians (North Caspian Sea, Russia) and other geographically close populations like Siberian Mansi, Buryats and other Iranians. New extended HLA haplotypes have been found, such as: A∗31:01-B∗35:01-DRB1∗15:01-DQB1∗03:01, A∗01:01-B∗35:01-DRB1∗03:01-DQB1∗02:01. Relationships of Turkmen with Kurgan (Gorgan) archaeological mounds, Scythians and Sarmatians are discussed. This study is also useful for a future transplantation Gorgan waiting list, Gorgan HLA and disease epidemiology and HLA pharmacogenomics. © 2015 Informa Healthcare USA, Inc.

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Ali Akbar Amirzargar (5)

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Style	Citing Format
MLA	Rey D, et al.. "Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology." Immunological Investigations, vol. 44, no. 1, 2015, pp. 88-100.
APA	Rey D, Amirzargar A, Areces C, Enriquezdesalamanca M, Marco J, Abdelfatahkhalil S, Fernandezhonrado M, Muniz E, Martinvilla JM, Arnaizvillena A (2015). Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology. Immunological Investigations, 44(1), 88-100.
Chicago	Rey D, Amirzargar A, Areces C, Enriquezdesalamanca M, Marco J, Abdelfatahkhalil S, Fernandezhonrado M, Muniz E, Martinvilla JM, Arnaizvillena A. "Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology." Immunological Investigations 44, no. 1 (2015): 88-100.
Harvard	Rey D et al. (2015) 'Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology', Immunological Investigations, 44(1), pp. 88-100.
Vancouver	Rey D, Amirzargar A, Areces C, Enriquezdesalamanca M, Marco J, Abdelfatahkhalil S, et al.. Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology. Immunological Investigations. 2015;44(1):88-100.
BibTex	@article{ author = {Rey D and Amirzargar A and Areces C and Enriquezdesalamanca M and Marco J and Abdelfatahkhalil S and Fernandezhonrado M and Muniz E and Martinvilla JM and Arnaizvillena A}, title = {Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology}, journal = {Immunological Investigations}, volume = {44}, number = {1}, pages = {88-100}, year = {2015} }
RIS	TY - JOUR AU - Rey D AU - Amirzargar A AU - Areces C AU - Enriquezdesalamanca M AU - Marco J AU - Abdelfatahkhalil S AU - Fernandezhonrado M AU - Muniz E AU - Martinvilla JM AU - Arnaizvillena A TI - Gorgan (Turkmen in Iran) Hla Genetics: Transplantation, Pharmacogenomics and Anthropology JO - Immunological Investigations VL - 44 IS - 1 SP - 88 EP - 100 PY - 2015 ER -

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