Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Magnetically Recoverable Graphene-Based Nanoparticles for the One-Pot Synthesis of Acridine Derivatives Under Solvent-Free Conditions Publisher



Mousavi SR1 ; Rashidi Nodeh H2 ; Foroumadi A1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medicinal Chemistry, Faculty of Pharmacy and The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Food science & Technology, Faculty of Food Industry and Agriculture, Standard Research Institute (SRI), Karaj, Iran

Source: Polycyclic Aromatic Compounds Published:2021


Abstract

Acridine derivatives were synthesized by reaction of dimedone, aromatic amines/ammonium acetate and various aromatic aldehydes in the presence of a new and green graphene oxide incorporated strontium magnetic nanocatalyst (MSrGO NCs) under solvent-free conditions. This methodology offers many advantages including operational simplicity, good to excellent yields (up to 97%), short reaction times, the remarkable magnetic property of the nanocomposite, and easy separation of the nanocatalyst from the reaction mixture by magnetic decantation and reused several times without significant loss of catalytic activity. © 2019 Taylor & Francis Group, LLC.