Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment

Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment Publisher Pubmed

Razi S^{1, 2} ; Baradaran Noveiry B^{3, 4} ; Keshavarzfathi M^{1, 5, 6} ; Rezaei N^{6, 7, 8}

Show Affiliations

1. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran
2. Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3. Division of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States
4. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Baltimore, MD, United States
5. Studentsâ€™ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
6. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
7. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
8. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Sheffield, United Kingdom

Source: Cytokine Published:2019

Abstract

Colorectal cancer (CRC) is one of the most common types of cancer in the world. Several factors contribute to the development of this cancer. Tumor formation in colon triggers immune responses such as immune cells proliferation, phenotype alteration, cytokine synthesis and release, which lead to IL-17 producing T cells, the differentiated CD4+ T cells i.e. T helper 17. IL-17 is a pro-inflammatory cytokine, which its level is up regulated in serum and tissues of CRC patients. Several studies have shown that IL-17 has an important role in metastasis and prognosis of CRC. The aim of this review is to summarize the role of this cytokine in tumorigenesis, angiogenesis and metastasis of CRC and discuss its value in diagnosis, prognosis and treatment of CRC. © 2019 Elsevier Ltd

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Nima Rezaei (1)

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Style	Citing Format
MLA	Razi S, et al.. "Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment." Cytokine, vol. 116, no. , 2019, pp. 7-12.
APA	Razi S, Baradaran Noveiry B, Keshavarzfathi M, Rezaei N (2019). Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment. Cytokine, 116(), 7-12.
Chicago	Razi S, Baradaran Noveiry B, Keshavarzfathi M, Rezaei N. "Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment." Cytokine 116, no. (2019): 7-12.
Harvard	Razi S et al. (2019) 'Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment', Cytokine, 116(), pp. 7-12.
Vancouver	Razi S, Baradaran Noveiry B, Keshavarzfathi M, Rezaei N. Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment. Cytokine. 2019;116():7-12.
BibTex	@article{ author = {Razi S and Baradaran Noveiry B and Keshavarzfathi M and Rezaei N}, title = {Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment}, journal = {Cytokine}, volume = {116}, number = {}, pages = {7-12}, year = {2019} }
RIS	TY - JOUR AU - Razi S AU - Baradaran Noveiry B AU - Keshavarzfathi M AU - Rezaei N TI - Il-17 and Colorectal Cancer: From Carcinogenesis to Treatment JO - Cytokine VL - 116 IS - SP - 7 EP - 12 PY - 2019 ER -

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