Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Association Between Healthy Diet Indicator and Phytochemical Index With Prostate Cancer Odds Ratio: A Case-Control Study Publisher Pubmed



Mahmoodi M1, 2 ; Mohammadi F1, 2 ; Rajabzadehdehkordi M1, 3 ; Jalilpiran Y4 ; Makhtoomi M1, 5 ; Nouri M6 ; Faghih S3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
  3. 3. Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Clinical Nutrition, School of Nutritional Science and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Cancer Research Center, Health Research Institute, Babol University of Medical sciences, Babol, Iran

Source: Journal of Health, Population and Nutrition Published:2024


Abstract

Background and objective: Healthy diets and diets rich in phytochemicals can have health-promoting benefits in prostate cancer. Therefore, this study aimed to explore the possible association between Healthy Diet Indicator (HDI) and Phytochemical Index (PI) with prostate cancer odds ratio. Methods: This is a case-control study conducted in Shiraz, Iran, involving 62 newly diagnosed prostate cancer cases and 63 hospital-based controls. The study collected demographic and anthropometric data, as well as dietary intake information via a semi-quantitative food frequency questionnaire. Logistic regression models were employed to evaluate the association between HDI and PI with prostate cancer. Results: The study included 120 participants and found that individuals with higher HDI and PI scores had a lower odds ratio of prostate cancer (HDI: odds ratio (OR): 0.322 – confidence interval (CI) 95%: 0.14–0.700 - PI: OR: 0.426 - CI 95%: 0.204–0.888). After adjusting for potential confounders, a lower odds ratio of prostate cancer was observed specifically among those with higher HDI scores (OR: 0.376 - CI 95%: 0.163–0.868). Conclusion: The findings of the present study suggest that adopting healthier dietary habits rich in dietary phytochemicals could be effective in preventing and halting the progression of prostate cancer. © The Author(s) 2024.
Related Docs
View other Related Docs
1. Dietary Phytochemical Index Is Favorably Associated With Oxidative Stress Status and Cardiovascular Risk Factors in Adults With Obesity, Scientific Reports (2023)
2. The Association Between Healthy and Unhealthy Dietary Indices With Prostate Cancer Risk: A Case-Control Study, Journal of Health, Population and Nutrition (2024)
3. Dietary Phytochemical Index and Its Relationship With Diabetic Sensorimotor Polyneuropathy: A Case-Control Study, Scientific Reports (2024)
4. Association Between Dietary Phytochemical Index and Breast Cancer: A Case–Control Study, Breast Cancer (2021)
5. Dietary Intake of Phytochemicals in Association With Irritable Bowel Syndrome in Adults, Clinical Nutrition ESPEN (2023)
6. Association of Dietary Phytochemical Index With Cardiometabolic Risk Factors a Systematic Review and Meta-Analysis on Observational Studies, International Journal for Vitamin and Nutrition Research (2023)
7. Association of Dietary Phytochemical Index and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2019)
8. The Relation Between Dietary Phytochemical Index and Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2023)
Experts (# of related papers)
View all Related Experts
Ahmad Esmaillzadeh (5)
Somayyeh Asghari (3)
Other Related Docs
9. The Association Between Ultra-Processed Foods Intake and the Odds of Prostate Cancer: A Case–Control Study, Journal of Health, Population and Nutrition (2025)
10. Higher Dietary Phytochemical Index Is Associated With Lower Odds of Knee Osteoarthritis, Scientific Reports (2022)
11. Association of the Dietary Phytochemical Index With General and Central Obesity in a Sample of Iranian Adults, Journal of Functional Foods (2021)
12. Dietary Phytochemical Index in Relation to Metabolic Health Status, Serum Adropin, and Brain-Derived Neurotrophic Factor Levels in Adults, Current Developments in Nutrition (2024)
13. Dietary Phytochemical Index and Benign Breast Diseases: A Case–Control Study, Nutrition and Cancer (2020)
14. The Association Between Dietary Diversity Score and Risk of Prostate Cancer: (A Case-Control Study), Nutrition and Cancer (2022)
15. The Relationship Between Dietary Phytochemical Index and Novel Anthropometric Indices and the Severity of Diabetic Foot Ulcers in Adults With Type 2 Diabetes: A Cross-Sectional Study, BMC Endocrine Disorders (2024)
16. The Relationship Between Dietary Phytochemical Index and Resting Metabolic Rate Mediated by Inflammatory Factors in Overweight and Obese Women: A Cross-Sectional Study, BMC Women's Health (2022)
17. Dietary Inflammatory Index and Site-Specific Cancer Risk: A Systematic Review and Dose-Response Meta-Analysis, Advances in Nutrition (2018)
18. Nutrition Knowledge, Attitudes, and Practice Towards Breast Cancer Prevention Among the Female Population of Iran University of Medical Science Students, Nutrition and Cancer (2019)
19. Adherence to Dietary Approaches to Stop Hypertension Eating Plan in Relation to Gastric Cancer, Nutrition Journal (2020)
20. Evaluation of Nuf2 and Gmnn Expression in Prostate Cancer: Potential Biomarkers for Prostate Cancer Screening, Reports of Biochemistry and Molecular Biology (2021)
21. Mediterranean Dietary Quality Index and Dietary Phytochemical Index Among Patients Candidate for Coronary Artery Bypass Grafting (Cabg) Surgery, BMC Cardiovascular Disorders (2017)
22. Higher Dietary Phytochemical Index Is Associated With Anthropometric Indices in Children and Adolescents: The Weight Disorders Survey of the Caspian-Iv Study, International Journal for Vitamin and Nutrition Research (2021)
23. Higher Intake of Phytochemical-Rich Foods Is Inversely Related to Prediabetes: A Case-Control Study, International Journal of Preventive Medicine (2018)
24. Adherence to Mediterranean Dietary Quality Index and Risk of Breast Cancer in Adult Women: A Case-Control Study, BMC Women's Health (2023)
25. Dietary Patterns and Dietary Phytochemical Index Are Associated With Major Depression Disorder in Females: A Case–Control Study; [Los Patrones Alimentarios Y El Indice De Fitoquimicos Alimentarios Estan Asociados Al Trastorno De Depresion Mayor En Las Mujeres: Estudio Caso-Control], Psiquiatria Biologica (2024)
26. Association of Dietary Phytochemical Index With Metabolic Markers, Serum Asymmetric Dimethylarginine and Atherogenic Indices in Patients With Polycystic Ovary Syndrome, Nutrition and Metabolism (2025)
27. Population Attributable Fraction of Dietary Risk Factors for Cancer Mortality With a Focus on Gastrointestinal Cancers in a Population Based Cohort Study, Scientific Reports (2025)
28. Empirically Derived Dietary Patterns in Relation to Psychological Disorders, Public Health Nutrition (2016)
29. Prostate Cancer in Iran: An Epidemiological Review, World Cancer Research Journal (2019)
30. Interaction Between the Dietary Indices and Ppar-Γ Pro12ala Gene Variants on Cardiovascular Risk Factors in Patients With Type 2 Diabetes Mellitus, International Journal of Clinical Practice (2021)
31. Major Dietary Patterns in Relation to Demographic and Socio-Economic Status and Food Insecurity in Two Iranian Ethnic Groups Living in Urmia, Iran, Public Health Nutrition (2016)
32. Gastric Cancer in Iran: An Overview of Risk Factors and Preventive Measures, Archives of Iranian Medicine (2021)
33. Association of Dietary Phytochemical Index and Anthropometric Risk Factors With Non-Alcoholic Fatty Liver Disease in People With Diabetes, Iranian Journal of Nutrition Sciences and Food Technology (2023)
34. Decreasing Trend of Blood Lipid Profile in Type 2 Diabetes: Not a Promising Change in Hdl-C, a Serial Cross-Sectional Study, PLoS ONE (2023)
35. Dietary Phytochemical Index Associated With Cardiovascular Risk Factor in Patients With Type 1 Diabetes Mellitus, BMC Cardiovascular Disorders (2021)
36. Population Attributable Proportion and Number of Cancer Cases Attributed to Potentially Modifiable Risk Factors in Iran in 2020, International Journal of Cancer (2023)
37. Dietary Soluble, Insoluble, and Total Fiber Intake and Their Dietary Sources in Association With Breast Cancer, BMC Public Health (2024)
38. Association Between Adhering to a Dietary Approach to Stop Hypertension and Risk of Colorectal Cancer: A Systematic Review and Meta-Analysis, BMC Gastroenterology (2025)
39. Increased Inflammatory Potential of Diet Is Associated With Increased Risk of Prostate Cancer in Iranian Men, International Journal for Vitamin and Nutrition Research (2016)
40. Dietary Fiber and Aging, Nutrients and Nutraceuticals for Active and Healthy Ageing (2020)
41. Interaction Between Cetp Taq1b Polymorphism and Hei, Dqi and Dpi on Metabolic Biomarkers in Patients With Type 2 Diabetes, Journal of Human Nutrition and Dietetics (2022)
42. Dietary Antioxidant Capacity Indices Are Negatively Correlated to Ldl-Oxidation in Adults, International Journal of Clinical Practice (2023)
43. Association of the Dietary Phytochemical Index With Circadian Rhythm and Mental Health in Overweight and Obese Women: A Cross-Sectional Study, Clinical Nutrition ESPEN (2022)
44. The Potential Causal Effect of the Pre-Pregnancy Dietary Phytochemical Index on Gestational Diabetes Mellitus: A Prospective Cohort Study, BMC Pregnancy and Childbirth (2024)
45. Adherence to the Mediterranean Diet in Relation to Gastric Cancer in Afghanistan, Frontiers in Nutrition (2022)
46. Dietary Energy Density and Risk of Prostate Cancer: (A Case–Control Study), Clinical Nutrition ESPEN (2021)
47. Dietary Quality Indices Modify the Effects of Apolipoprotein B Polymorphisms on Biochemical and Anthropometric Factors in Type 2 Diabetes Mellitus, Scientific Reports (2021)
48. The Association Between the Dietary Inflammatory Index and Multiple Myeloma: A Case–Control Study, Scientific Reports (2025)