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The Association Between Planetary Health Diet Index and the Risk of Colorectal Cancer: A Case-Control Study Publisher Pubmed



Mohammadi F1 ; Alijani S2 ; Abdollahi N3 ; Mashoufi A5 ; Nouri M6 ; Soltanii M7 ; Shateri Z8 ; Rashidkhani B9
Authors
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Authors Affiliations
  1. 1. Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Student Research Committee, Department of Biochemistry and Diet Therapy, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Nutrition and Food Security Research Center, Department of Nutrition, Health Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  4. 4. Department of Nutrition, Health Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  5. 5. Department of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
  7. 7. Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Nutrition and Biochemistry, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  9. 9. Department of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Scientific Reports Published:2024


Abstract

Background Despite the beneficial effects of a plant-based diet on colorectal cancer (CRC), no study has yet investigated the relationship between a Planetary Health Diet Index (PHDI) and CRC in the Iranian population. Therefore, the present case-control study aimed to assess the relationship between this index and CRC. Methods The current research was conducted on 71 patients with CRC (case group) and 142 (control group) admitted to hospitals in Tehran, Iran. The PHDI (0-150 points) was calculated based on a semi-quantitative food frequency questionnaire. Conditional logistic regression was applied to evaluate the association between CRC and PHDI and its sub-scores. Results After adjusting for the role of potential confounders, lower odds of CRC were observed in the second tertile of the total ratio score (odds ratio (OR) = 0.334; 95% confidence interval (CI): 0.127–0.878, P = 0.026) and the last tertile of PHDI (OR = 0.407; 95% CI: 0.183–0.907, P = 0.028), total adequacy score (OR = 0.261; 95% CI: 0.110–0.622, P = 0.002), and total moderation score (OR = 0.380; 95% CI: 0.162–0.891, P = 0.026) in comparison to the first tertile of each index. Conclusions The current study’s findings indicated a reverse relationship between PHDI, total adequacy, moderation, and ratio scores with the CRC odds. However, it is suggested that more research be performed in this field in the future to confirm the results of this study. © The Author(s) 2024.
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