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Vaccines, Adjuvants, and Delivery Systems Publisher



Keshavarzfathi M1, 2, 3 ; Rezaei N3, 4, 5
Authors
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Authors Affiliations
  1. 1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives Published:2019


Abstract

Vaccines have been used as a preventive modality against infectious disease for a long time. The application of vaccines to treat the diseases, which have interactions with the immune system, have revealed a new concept of immunotherapy, known as therapeutic vaccines. Many efforts have been made to utilize this modality in the most efficient way. To optimize the current vaccines, understanding the determinants such as selection of the appropriate antigens, combination of effective adjuvants, application of a delivery system, and administration through the proper route are necessary. In this chapter, we will discuss the mentioned determinants to prepare the background for extending the knowledge of vaccinology. © 2019 Nima Rezaei and Mahsa Keshavarz-Fathi Published by Elsevier Ltd. All rights reserved.
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