Nanotherapeutics in the Treatment of Cancer: Transforming Cancer Care Publisher



Rad M K ; Razani E ; Bashash D
Source: European Journal of Cancer Care Published:2026

Abstract

Nanotechnology is revolutionizing oncological interventions through nanotherapeutics, which employ nanoparticles (NPs) to significantly increase treatment precision and efficacy. These NP vectors deliver anticancer agents directly to tumors, reducing damage to healthy cells by utilizing the established enhanced permeability and retention (EPR) effect. In response to targeted biochemical signals, NPs ensure precise drug release within tumors. Additionally, they function as contrast agents to improve cancer imaging and diagnostics, facilitating early diagnosis and the development of personalized therapies. NP-based combination therapies effectively combat drug resistance by delivering multiple therapeutic agents targeting diverse molecular pathways. Nanomedicines provide accurate drug delivery in blood cancers, reducing side effects and potentially enhancing hematopoietic stem cell transplantation. Furthermore, NPs modulate intracellular signaling in hematological cancers, offering opportunities for pioneering treatments. This article highlights the multifaceted roles of NPs in advancing cancer treatment, pointing toward significant improvements and future research directions. © The Author(s).