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Zeolites for Theranostic Applications Publisher Pubmed



Khodadadi Yazdi M1 ; Zarrintaj P2 ; Hosseiniamoli H3 ; Mashhadzadeh AH1 ; Saeb MR4 ; Ramsey JD2 ; Ganjali MR1, 5 ; Mozafari M6, 7
Authors
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Authors Affiliations
  1. 1. Center of Excellence in Electrochemistry, School of Chemistry, College of Science, University of Tehran, Tehran, Iran
  2. 2. School of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, 74078, OK, United States
  3. 3. Western Sydney University, Centre for Infrastructure Engineering, Sydney, 2747, Australia
  4. 4. Department of Resin and Additives, Institute for Color Science and Technology, Tehran, Iran
  5. 5. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran
  7. 7. Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

Source: Journal of Materials Chemistry B Published:2020


Abstract

Theranostic platforms bring about a revolution in disease management. During recent years, theranostic nanoparticles have been utilized for imaging and therapy simultaneously. Zeolites, because of their porous structure and tunable properties, which can be modified with various materials, can be used as a delivery agent. The porous structure of a zeolite enables it to be loaded and unloaded with various molecules such as therapeutic agents, photosensitizers, biological macromolecules, MRI contrast agents, radiopharmaceuticals, near-infrared (NIR) fluorophores, and microbubbles. Furthermore, theranostic zeolite nanocarriers can be further modified with targeting ligands, which is highly interesting for targeted cancer therapies. © The Royal Society of Chemistry.
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