A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study

A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study Publisher Pubmed

Ghazali HS¹ ; Askari E² ; Seyfoori A² ; Naghib SM¹

Show Affiliations

1. Nanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology, Tehran, Iran
2. Biomaterials and Tissue Engineering Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran

Source: Scientific Reports Published:2023

Abstract

Light-based hydrogel crosslinking is a new approach in rapid and high-resolution 3D printing; however, using this method in tissue engineering is challenging due to the toxicity of photoinitiators, their solvents, and their low efficiency. Herein, a novel, water-soluble photoinitiator with high efficiency in light-based 3D printing is introduced. Low-cost photoinitator, 2,4,6-trimethylbenzoylphenyl phosphinate, is converted into nanoparticles via a microemulsion method and dispersed in water. Cell toxicity assays were performed to prove that these nanoparticles are non-toxic and can be used in biomedical applications. Finally, the nanoparticles were utilized in the high-accuracy 3D printing of hydrogels. The results of this study indicate that these particles are potent to be used in bioprinting. © 2023, The Author(s).

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Saeid Amanpour (1)

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Style	Citing Format
MLA	Ghazali HS, et al.. "A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study." Scientific Reports, vol. 13, no. 1, 2023, pp. -.
APA	Ghazali HS, Askari E, Seyfoori A, Naghib SM (2023). A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study. Scientific Reports, 13(1), -.
Chicago	Ghazali HS, Askari E, Seyfoori A, Naghib SM. "A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study." Scientific Reports 13, no. 1 (2023): -.
Harvard	Ghazali HS et al. (2023) 'A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study', Scientific Reports, 13(1), pp. -.
Vancouver	Ghazali HS, Askari E, Seyfoori A, Naghib SM. A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study. Scientific Reports. 2023;13(1):-.
BibTex	@article{ author = {Ghazali HS and Askari E and Seyfoori A and Naghib SM}, title = {A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study}, journal = {Scientific Reports}, volume = {13}, number = {1}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Ghazali HS AU - Askari E AU - Seyfoori A AU - Naghib SM TI - A High-Absorbance Water-Soluble Photoinitiator Nanoparticle for Hydrogel 3D Printing: Synthesis, Characterization and in Vitro Cytotoxicity Study JO - Scientific Reports VL - 13 IS - 1 SP - EP - PY - 2023 ER -

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