A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications

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A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications Publisher

Samani S¹ ; Bonakdar S² ; Farzin A¹ ; Hadjati J¹ ; Azami M¹

Source: International Journal of Polymeric Materials and Polymeric Biomaterials Published:2021

Abstract

In this study, we introduced a novel and modified method to synthesize photocrosslinkable chitosan hydrogel. Three methacrylated samples under two concentrations of methacrylic anhydride and using EDC/NHS as a crosslinker were prepared. Methacrylated chitosan obtained under controlled conditions and using EDC/NHS had significant coupling efficiency and capacity of gel formation compared to other samples. Diluted culture media provided a favorable solubility condition for methacrylated chitosan and could be tolerated by cells during gelation time. The hydrogels included interconnected pores ranging 100–300 µm and swelling ratios of 40–400%. The results opened the new aspects for developing novel biomaterials in cell-based therapies. © 2020 Taylor & Francis Group, LLC.

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Style	Citing Format
MLA	Samani S, et al.. "A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications." International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 70, no. 10, 2021, pp. 730-741.
APA	Samani S, Bonakdar S, Farzin A, Hadjati J, Azami M (2021). A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications. International Journal of Polymeric Materials and Polymeric Biomaterials, 70(10), 730-741.
Chicago	Samani S, Bonakdar S, Farzin A, Hadjati J, Azami M. "A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications." International Journal of Polymeric Materials and Polymeric Biomaterials 70, no. 10 (2021): 730-741.
Harvard	Samani S et al. (2021) 'A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications', International Journal of Polymeric Materials and Polymeric Biomaterials, 70(10), pp. 730-741.
Vancouver	Samani S, Bonakdar S, Farzin A, Hadjati J, Azami M. A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications. International Journal of Polymeric Materials and Polymeric Biomaterials. 2021;70(10):730-741.
BibTex	@article{ author = {Samani S and Bonakdar S and Farzin A and Hadjati J and Azami M}, title = {A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications}, journal = {International Journal of Polymeric Materials and Polymeric Biomaterials}, volume = {70}, number = {10}, pages = {730-741}, year = {2021} }
RIS	TY - JOUR AU - Samani S AU - Bonakdar S AU - Farzin A AU - Hadjati J AU - Azami M TI - A Facile Way to Synthesize a Photocrosslinkable Methacrylated Chitosan Hydrogel for Biomedical Applications JO - International Journal of Polymeric Materials and Polymeric Biomaterials VL - 70 IS - 10 SP - 730 EP - 741 PY - 2021 ER -

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