The Association Between Continuous Metabolic Syndrome Score and Its Components With Electrocardiographic Abnormalities in Community-Dwelling Older Adults: The Bushehr Elderly Health (Beh) Program Publisher Pubmed



Farhadi A¹ ; Emamat H¹ ; Nemati R^{2, 3} ; Marzban M^{4, 5} ; Shafiee G⁶ ; Nabipour I⁷ ; Ostovar A⁸ ; Jalaliyan Z⁹ ; Malekizadeh H⁹ ; Larijani B¹⁰ Show Affiliations
Source: BMC Cardiovascular Disorders Published:2024

Abstract

Background: Metabolic syndrome (MetS) known as a risk factor for cardiovascular diseases (CVDs) has developed into a major source of health issue, especially for the elderly. In the present study, we investigated the association between continuous MetS (cMetS) score and its components with electrocardiographic (ECG) abnormalities in the community-dwelling older adults. Methods: This cross-sectional study is derived from the second phase of BEH cohort study which is conducted on individuals aged over 60 years old. Standard 12-lead ECGs were recorded and coded by qualified physicians and continuous values of metabolic syndrome risk scores (cMetS) were measured. Data regarding socio-demographic, medical history, and lifestyle variables were collected by trained interviewers. The multinomial regression analysis was used to investigate the relationship between cMetS and its components with ECG abnormalities in the included participants. Results: 2426 individuals (mean age ± standard deviation: 69.30 ± 6.33 years) were included in the final analysis. Overall, 22.5% of the participants showed ECG abnormalities. Among these, 8.0% (n = 139) of participants had minor and 14.6% (n = 354) had major ECG abnormalities. In the final models, cMetS (OR = 1.04), mean arterial pressure (MAP((OR = 1.01), and higher fasting blood glucose (FBG) (OR = 1.01) increased the risk of ECG abnormalities (p < 0.05). Also, cMetS (OR = 1.05) and MAP (OR = 1.02) were associated with an increased risk of major ECG abnormalities (p < 0.05). Conclusion: MetS and MAP were significantly associated with ECG abnormalities. The results of the present study suggest that ECG screening in the older population with MetS could potentially help to detect those at the higher risk of CVDs. © 2024, The Author(s).