An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting

An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting Publisher

Bagheri Saed A¹ ; Behravesh AH¹ ; Hasannia S^{2, 3} ; Akhoundi B¹ ; Hedayati SK¹ ; Gashtasbi F³

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1. Additive Manufacturing Laboratory, Faculty of Mechanical Engineering, Tarbiat Modares University, Tehran, Iran
2. Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran
3. Nova Teb Research Laboratory, Dental Equipment and Bio-material Technology Incubation Center, Tehran, Iran

Source: European Polymer Journal Published:2020

Abstract

The main aim of this study was to assess the influence of adding BCP particles on enhancing essential properties of PLLA matrix scaffolds for bone grafting purpose. Poly L-lactic acid (PLLA)/biphasic calcium phosphate (BCP) scaffolds were fabricated via a digital light processing (DLP) 3D printer, with 70% porosity and 600 µm pore size. DLP method was utilized to generate scaffolds with sophisticated geometry, and the bio-composite material was introduced to benefit from positive aspects of polymeric/inorganic substances for bone regeneration. The selected BCP contents were 22.5, and 45 wt% compared with the control specimens with no content. Morphology, exact amount of BCP concentration as well as their distribution were assessed using computerized tomography (µ-CT), thermogravimetry analysis (TGA) and scanning electron microscopy (SEM). Moreover, in vitro biodegradability, cell viability and attachment of the specimens were also investigated. The results showed that in spite of decreasing effect of BCP particles on the mechanical properties of the printed scaffolds, cell adherence and hydrophilicity of the samples were considerably improved. Moreover, a 22.5 wt% of BCP content was found to be an optimum amount to preserve the mechanical properties during biodegradation. The paper showed the effectiveness of adding BCP particles as a biocompatible ceramic to enhance properties of the scaffolds for dental bone regeneration. © 2020 Elsevier Ltd

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Style	Citing Format
MLA	Bagheri Saed A, et al.. "An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting." European Polymer Journal, vol. 141, no. , 2020, pp. -.
APA	Bagheri Saed A, Behravesh AH, Hasannia S, Akhoundi B, Hedayati SK, Gashtasbi F (2020). An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting. European Polymer Journal, 141(), -.
Chicago	Bagheri Saed A, Behravesh AH, Hasannia S, Akhoundi B, Hedayati SK, Gashtasbi F. "An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting." European Polymer Journal 141, no. (2020): -.
Harvard	Bagheri Saed A et al. (2020) 'An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting', European Polymer Journal, 141(), pp. -.
Vancouver	Bagheri Saed A, Behravesh AH, Hasannia S, Akhoundi B, Hedayati SK, Gashtasbi F. An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting. European Polymer Journal. 2020;141():-.
BibTex	@article{ author = {Bagheri Saed A and Behravesh AH and Hasannia S and Akhoundi B and Hedayati SK and Gashtasbi F}, title = {An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting}, journal = {European Polymer Journal}, volume = {141}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Bagheri Saed A AU - Behravesh AH AU - Hasannia S AU - Akhoundi B AU - Hedayati SK AU - Gashtasbi F TI - An in Vitro Study on the Key Features of Poly L-Lactic Acid/Biphasic Calcium Phosphate Scaffolds Fabricated Via Dlp 3D Printing for Bone Grafting JO - European Polymer Journal VL - 141 IS - SP - EP - PY - 2020 ER -

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