Copper Supported Imidazolylpyridine Modified Spion As an Efficient Catalyst for Eco-Friendly, One-Pot and Green Synthesis of Novel (3-Cyanothiophen-2-Yl)-N-(Arylsulfonyl)Acetimidamide Derivatives Publisher Pubmed



Askarzadeh M¹ ; Adib M¹ ; Mahdavi M² Show Affiliations
Source: Current Organic Synthesis Published:2023

Abstract

Background: In this paper, a novel catalyst is synthesized and characterized by immobi-lizing copper onto imidazopyridine-modified superparamagnetic iron oxide nanoparticles (SPION). Methods: The catalyst is characterized by several methods, including TEM, SEM, ICP, DLS, and VSM. The catalytic activity of the catalyst is evaluated in the synthesis of thiosolfunamide. The synthesized catalyst showed very good activity in the mentioned reaction and performance for synthe-sizing the desired products in high isolated yields. Results: For the synthesis of the products, sequential transformations enable the facile synthesis of complex target molecules from simple building blocks in a single preparative step. Conclusion: The reaction can be performed with a high yield using water and ethanol as the reaction green solvent using terminal alkynes and sulfonyl azides as starting materials. The reusability of the catalyst was tested, and the results proved high reusability of the catalyst. © 2023 Bentham Science Publishers.