Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis

Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis Publisher

Haerian MS¹ ; Haerian BS² ; Molanaei S³ ; Kosari F⁴ ; Sabeti S⁵ ; Bidarizerehpoosh F⁵ ; Abdolali E⁶ ; Zali MR⁷

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1. Bone and Joint Reconstruction Research Center, Shafa Yahyaeian Orthopedics Hospital, Iran University of Medical Sciences, Tehran, Iran
2. Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3. Department of Pathology, Milad Hospital, Tehran, Iran
4. Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
5. Department of Pathology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6. Department of Pathology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7. Gastroenterology and Liver Diseases Research Center (GLDRC), Shahid Beheshti University of Medical Science, Tehran, Iran

Source: Pharmacogenomics Published:2016

Abstract

Several studies have investigated whether MTHFR rs1801133 polymorphism contributes to risk of colorectal cancer (CRC), however the results are inconclusive. Aim: The purpose of this study was to investigate this hypothesis in a case-control study and meta-analysis in Iranian population. Materials & methods: This polymorphism was genotyped in the 2421 subjects (46% CRC patients) from Tehran. Meta-analysis was performed for determining the risk effect size of this polymorphism on CRC. Results: Both case-control study and meta-analysis showed no association between rs1801133 and CRC risk or its features. Conclusion: This study failed to identify an association between the rs1801133 and susceptibility to CRC in Iranian population. © 2016 Future Medicine Ltd.

2. Mtrr Rs1801394 and Its Interaction With Mthfr Rs1801133 in Colorectal Cancer: A Case-Control Study and Meta-Analysis, Pharmacogenomics (2017)

Experts (# of related papers)

Farid Kosari (1)

Style	Citing Format
MLA	Haerian MS, et al.. "Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis." Pharmacogenomics, vol. 17, no. 17, 2016, pp. 1957-1965.
APA	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, Abdolali E, Zali MR (2016). Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis. Pharmacogenomics, 17(17), 1957-1965.
Chicago	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, Abdolali E, Zali MR. "Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis." Pharmacogenomics 17, no. 17 (2016): 1957-1965.
Harvard	Haerian MS et al. (2016) 'Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis', Pharmacogenomics, 17(17), pp. 1957-1965.
Vancouver	Haerian MS, Haerian BS, Molanaei S, Kosari F, Sabeti S, Bidarizerehpoosh F, et al.. Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis. Pharmacogenomics. 2016;17(17):1957-1965.
BibTex	@article{ author = {Haerian MS and Haerian BS and Molanaei S and Kosari F and Sabeti S and Bidarizerehpoosh F and Abdolali E and Zali MR}, title = {Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis}, journal = {Pharmacogenomics}, volume = {17}, number = {17}, pages = {1957-1965}, year = {2016} }
RIS	TY - JOUR AU - Haerian MS AU - Haerian BS AU - Molanaei S AU - Kosari F AU - Sabeti S AU - Bidarizerehpoosh F AU - Abdolali E AU - Zali MR TI - Mthfr Rs1801133 Polymorphism and Susceptibility to Colorectal Cancer in Iranian Population: Evidence of a Case-Control Study and Meta-Analysis JO - Pharmacogenomics VL - 17 IS - 17 SP - 1957 EP - 1965 PY - 2016 ER -

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