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Putative Therapeutic Impact of Inflammasome Inhibitors Against Covid-19-Induced Ards Publisher Pubmed



Nabavi SF1 ; Sahebnasagh A2 ; Shahbazi A3 ; Nabavi SM1 ; Azimi S4 ; Kashani MK5 ; Habtemariam S6 ; Rahmani M7 ; Badiee M7 ; Hashemi J8 ; Saghafi F9 ; Amini K10 ; Azimi M11 ; Rezabakhsh A12
Authors

Source: Current Medicinal Chemistry Published:2023


Abstract

Given the importance of COVID-19-induced ARDS, recently, researchers have strived to determine underlying mechanisms involved in the inflammatory responses. In this regard, inflammasomes possess a distinct priority for cytokine storm occurrence and, subsequently, ARDS progression in ill patients with SARS-CoV-2 infection. In this minireview, the characteristics of known inflammasome inhibitors and designed research in this field were concretely deciphered. © 2023 Bentham Science Publishers.
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