Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease

Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease

Fallahi GH¹ ; Khatami GR¹ ; Esmailzadehha N^{2, 3} ; Najafi M¹ ; Farahmand F¹ ; Motamed F¹ ; Khodadad A¹ ; Rezaei N^{4, 5} ; Modarresi MR^{6, 7} ; Qorbani M⁸ ; Bagherian R⁹

Show Affiliations

1. Research Center for Pediatric Gastroenterology and Hepatology, Childrenâ€™s Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran
2. Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
3. Department of Epidemiology, School of Health, Iran University of Medical Sciences, Tehran, Iran
4. Research Center for Immunodeficiencies, Childrenâ€™s Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran
5. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
6. Department of Pediatric Pulmonary Diseases, Tehran University of Medical Sciences, Tehran, Iran
7. Pediatric Respiratory Diseases Education and Research Network (PRDERN), Universal Scientific Education and Research Network (USERN), Tehran, Iran
8. Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran
9. Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran

Source: Acta Medica Iranica Published:2018

Abstract

There are controversies on the association of childhood allergic diseases with inflammatory bowel diseases (IBD). The aim of this study was to examine the association between food allergy, cow’s milk allergy (CMA), and asthma with pediatric IBD in Iranian population. This case-control study was conducted on 200 individuals less than 18-year-old (100 with IBD and 100 as control group). Medical records, clinical presentation, and laboratory and para-clinical findings related to food allergy, CMA, and asthma were reviewed for all participants in both groups and were recorded. Among 100 children with IBD, 40 had Crohn's disease, and 60 had ulcerative colitis. The frequency of food allergy, cow's milk allergy, and asthma in children with IBD was significantly higher than the control group (P<0.001). Asthma in children with Crohn's disease was significantly more prevalent than children with ulcerative colitis (P=0.008). Food allergy (OR: 22.1, 95% CI: 5.1-95.05, P<0.001), CMA (OR: 15, 95% CI: 3-67, P<0.001), and asthma (OR: 10, 95% CI: 3-37.05, P<0.001) were significantly associated with increased risk of IBD in children. Food allergy, CMA in infancy and asthma are more prevalent in children with different subtypes of IBD. The diagnosis of these risk factors is associated with increased risk of Crohn's disease and ulcerative colitis. © 2018 Tehran University of Medical Sciences. All rights reserved.

2. Feeding-Based Treatment of Allergic Proctocolitis and Associated Clinical Outcomes, Clinical Nutrition ESPEN (2020)

3. Early Onset Inflammatory Bowel Disease: Manifestations, Genetics and Diagnosis, Turkish Journal of Pediatrics (2019)

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Style	Citing Format
MLA	Fallahi GH, et al.. "Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease." Acta Medica Iranica, vol. 56, no. 5, 2018, pp. 329-333.
APA	Fallahi GH, Khatami GR, Esmailzadehha N, Najafi M, Farahmand F, Motamed F, Khodadad A, Rezaei N, Modarresi MR, Qorbani M, Bagherian R (2018). Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease. Acta Medica Iranica, 56(5), 329-333.
Chicago	Fallahi GH, Khatami GR, Esmailzadehha N, Najafi M, Farahmand F, Motamed F, Khodadad A, et al.. "Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease." Acta Medica Iranica 56, no. 5 (2018): 329-333.
Harvard	Fallahi GH et al. (2018) 'Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease', Acta Medica Iranica, 56(5), pp. 329-333.
Vancouver	Fallahi GH, Khatami GR, Esmailzadehha N, Najafi M, Farahmand F, Motamed F, et al.. Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease. Acta Medica Iranica. 2018;56(5):329-333.
BibTex	@article{ author = {Fallahi GH and Khatami GR and Esmailzadehha N and Najafi M and Farahmand F and Motamed F and Khodadad A and Rezaei N and Modarresi MR and Qorbani M and Bagherian R}, title = {Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease}, journal = {Acta Medica Iranica}, volume = {56}, number = {5}, pages = {329-333}, year = {2018} }
RIS	TY - JOUR AU - Fallahi GH AU - Khatami GR AU - Esmailzadehha N AU - Najafi M AU - Farahmand F AU - Motamed F AU - Khodadad A AU - Rezaei N AU - Modarresi MR AU - Qorbani M AU - Bagherian R TI - Association of Food Allergies, Cow’S Milk Allergy, and Asthma With Pediatric Inflammatory Bowel Disease JO - Acta Medica Iranica VL - 56 IS - 5 SP - 329 EP - 333 PY - 2018 ER -

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