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Prevalence of Retinal Pathologies in People Over 60 Years: The Tehran Geriatrics Eye Study Publisher



Mortazavi A1 ; Hashemi A2 ; Jamali A3 ; Hashemi H4 ; Aghamirsalim M5 ; Khabazkhoob M6
Authors
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Authors Affiliations
  1. 1. Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, 1416753955, Iran
  2. 2. Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, 1983963113, Iran
  3. 3. Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, 1545913487, Iran
  4. 4. Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, 1983963113, Iran
  5. 5. Translational Ophthalmology Research Center, Tehran University of Medical Sciences, Tehran, 1157715354, Iran
  6. 6. Department of Basic Sciences, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, 1968653111, Iran

Source: International Journal of Ophthalmology Published:2024


Abstract

• AIM: To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors. • METHODS: A cross-sectional study was conducted in Tehran using multistage cluster sampling. After selecting subjects aged 60 and over, optometric, and ophthalmic examinations were done. For retinal examination, a 90 D lens was used and indirect ophthalmoscopy was performed after instilling tropicamide drops. Biometry was done using the IOL Master for all participants. • RESULTS: Of 3791 people that were invited through cluster sampling, 3310 participated in the study (response rate=82%). The prevalence of retinal pigmented epithelium (RPE) change, drusen, geographic atrophy (GA), hypertensive retinopathy (HTR), nonproliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), choroidal neovascularization (CNV), central retinal artery occlusion (CRAO), myopic retinopathy (MR), branch retinal vein occlusion (BRVO), and central retinal vein occlusion (CRVO) was 27.42%, 11.08%, 4.52%, 3.03%, 4.05%, 0.54%, 0.82%, 0.39%, 0.20%, 0.49%, and 0.19%, respectively. After removing the effect of age, the odds of NPDR were 1.68 times higher in women compared to men (P=0.014). After removing the effect of sex, the odds of drusen, RPE change, GA, CNV, BRVO, and CRVO increased with age. • CONCLUSION: There is a higher prevalence of RPE change, drusen, GA, CNV and a lower prevalence of MR and CRAO in the elderly population of Tehran aged over 60y compared to global average values. Considering the correlation of most of the diseases with age and their effects on vision, attention should be paid to these diseases and the related screening programs to prevent vision impairment. © 2024 International Journal of Ophthalmology (c/o Editorial Office). All rights reserved.