The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm)

The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm) Publisher

Soltanieh S^{1, 2} ; Salavatizadeh M^{1, 2} ; Poustchi H³ ; Yari Z⁴ ; Mansour A⁵ ; Khamseh ME² ; Malek M⁶ ; Alaeishahmiri F² ; Hekmatdoost A¹

Show Affiliations

1. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
3. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
6. Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran

Source: Heliyon Published:2023

Abstract

Background & Objective: High prevalence of non-alcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus results in deleterious complications and morbidities related to both diseases. Thus, we aimed to investigate dietary and anthropometric risk factors for progression of Non-alcoholic Fatty Liver Disease (NAFLD) in diabetic people. Methods: Anthropometric, and dietary intakes, and hepatic steatosis and fibrosis were assessed in two hundred participants with type two diabetes (T2DM). Subjects with CAP score of more than 270 dB/m were considered to have NAFLD. Multivariable-adjusted ORs and 95% CIs were used to investigate the association between NAFLD and dietary inflammatory index (DII) score and anthropometric indices. Results: Participants in the highest tertile of DII had 2.41 (95% CI:1.16-4.97), 2,53 (95% CI: 1.04-6.16), 2.78 (95% CI: 1.09-7.13) times higher odds of developing NAFLD in comparison to the lowest tertile in crude, adjusted model 1 and 2, respectively. Among those with the highest relative to the lowest tertile of trunk-to-leg fat ratio (TLR), ORs and 95% CI were OR = 1.88, 95% CI = 0.9-3.91, and OR = 7.99, 95% CI = 2.43-26.26 in crude and full-adjusted models. Odds of NAFLD in the third tertile of metabolic score for visceral fat (METS-VF) was higher than the first tertile in crude (OR = 9.5, 95% CI = 4.01-22.46) and full-adjusted models (OR = 4.55, 95% CI = 1.46-14.2). Conclusions: In conclusion, this study highlighted an association between greater DII (pro-inflammatory diet) and higher NAFLD risk. Moreover, TLR and METS-VF are known as novel estimators of central obesity as a risk factor for NAFLD in diabetes. © 2023 The Authors

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Style	Citing Format
MLA	Soltanieh S, et al.. "The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm)." Heliyon, vol. 9, no. 3, 2023, pp. -.
APA	Soltanieh S, Salavatizadeh M, Poustchi H, Yari Z, Mansour A, Khamseh ME, Malek M, Alaeishahmiri F, Hekmatdoost A (2023). The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm). Heliyon, 9(3), -.
Chicago	Soltanieh S, Salavatizadeh M, Poustchi H, Yari Z, Mansour A, Khamseh ME, Malek M, Alaeishahmiri F, Hekmatdoost A. "The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm)." Heliyon 9, no. 3 (2023): -.
Harvard	Soltanieh S et al. (2023) 'The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm)', Heliyon, 9(3), pp. -.
Vancouver	Soltanieh S, Salavatizadeh M, Poustchi H, Yari Z, Mansour A, Khamseh ME, et al.. The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm). Heliyon. 2023;9(3):-.
BibTex	@article{ author = {Soltanieh S and Salavatizadeh M and Poustchi H and Yari Z and Mansour A and Khamseh ME and Malek M and Alaeishahmiri F and Hekmatdoost A}, title = {The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm)}, journal = {Heliyon}, volume = {9}, number = {3}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Soltanieh S AU - Salavatizadeh M AU - Poustchi H AU - Yari Z AU - Mansour A AU - Khamseh ME AU - Malek M AU - Alaeishahmiri F AU - Hekmatdoost A TI - The Association of Dietary Inflammatory Index (Dii) and Central Obesity With Non-Alcoholic Fatty Liver Disease (Nafld) in People With Diabetes (T2dm) JO - Heliyon VL - 9 IS - 3 SP - EP - PY - 2023 ER -

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