Micrornas in Cancer

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Mirzaei H¹ ; Rahimian N² ; Mirzaei HR³ ; Nahand JS⁴ ; Hamblin MR⁵

Source: Synthesis Lectures on Biomedical Engineering Published:2022

Abstract

The dysregulation of microRNAs in cancer was first reported in 2002, when a cluster of two microRNAs (miR16 and miR-15) was detected at chromosome 13q14.3, which had been proposed as one of the commonly eliminated genetic regions in chronic lymphocytic leukemia (CLL) patients [1]. The deletion of this miRNA cluster acts (at least partly) by increasing the expression level of the specific target of miR-15/16, which is the anti-apoptotic protein B cell lymphoma 2 (BCL2). It has been found that micro-RNAs can contribute to each cancer hallmark described by Hanahan and Weinberg [2], as well affecting the clinical progression of many cancers at different stages. © 2022, Springer Nature Switzerland AG.

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Style	Citing Format
MLA	Mirzaei H, et al.. "Micrornas in Cancer." Synthesis Lectures on Biomedical Engineering, vol. , no. , 2022, pp. 11-40.
APA	Mirzaei H, Rahimian N, Mirzaei HR, Nahand JS, Hamblin MR (2022). Micrornas in Cancer. Synthesis Lectures on Biomedical Engineering, (), 11-40.
Chicago	Mirzaei H, Rahimian N, Mirzaei HR, Nahand JS, Hamblin MR. "Micrornas in Cancer." Synthesis Lectures on Biomedical Engineering , no. (2022): 11-40.
Harvard	Mirzaei H et al. (2022) 'Micrornas in Cancer', Synthesis Lectures on Biomedical Engineering, (), pp. 11-40.
Vancouver	Mirzaei H, Rahimian N, Mirzaei HR, Nahand JS, Hamblin MR. Micrornas in Cancer. Synthesis Lectures on Biomedical Engineering. 2022;():11-40.
BibTex	@article{ author = {Mirzaei H and Rahimian N and Mirzaei HR and Nahand JS and Hamblin MR}, title = {Micrornas in Cancer}, journal = {Synthesis Lectures on Biomedical Engineering}, volume = {}, number = {}, pages = {11-40}, year = {2022} }
RIS	TY - JOUR AU - Mirzaei H AU - Rahimian N AU - Mirzaei HR AU - Nahand JS AU - Hamblin MR TI - Micrornas in Cancer JO - Synthesis Lectures on Biomedical Engineering VL - IS - SP - 11 EP - 40 PY - 2022 ER -

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