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Introduction on Challenges for Autoimmune Diseases Publisher



Yazdanpanah N1, 2, 3 ; Rezaei N2, 3, 4
Authors
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Authors Affiliations
  1. 1. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  4. 4. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Translational Autoimmunity: Challenges for Autoimmune Diseases: Volume 5 Published:2022


Abstract

Autoimmune diseases have remained a mysterious territory in medical sciences. Considering the unanswered questions concerning the ethiopathogenesis of autoimmune diseases, many challenges remained to be tackled in this field. The prevention, diagnosis, treatment, and prognosis of autoimmune diseases are affected by different factors; for instance, the specificity and sensitivity of most diagnostic tools as well as the therapeutic agents do not meet the expectations, while there is no validated marker for disease prediction or prognosis. Nevertheless, new fields of research including multiomics analysis, immunometabolism, genetic studies, and precision medicine could be promising tools to address the existing challenges in autoimmune diseases. © 2023 Elsevier Inc. All rights reserved.
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