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Autoimmune Diseases in Different Organs Publisher



Rezaei N1, 2, 3 ; Yazdanpanah N1, 3, 4
Authors
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Authors Affiliations
  1. 1. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  4. 4. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Translational Autoimmunity: Autoimmune Diseases in Different Organs Published:2022


Abstract

Organ-specific autoimmune diseases target specific tissues in the body. The produced autoantibodies, autoreactive immune cells, and immune complexes that mediate the pathophysiology of the disease differ based on the targeted tissue. Nevertheless, systemic autoimmune diseases could affect different tissues of the body by creating an inflammatory state in the body and triggering autoreactive immune components. In this chapter, important autoimmune manifestations in different tissues and physiological systems of the body are overviewed. © 2022 Elsevier Inc. All rights reserved.
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