Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline

Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline Publisher

Summary: Can a simple amino acid create new drugs? Research shows l-proline helps build diverse bioactive compounds, potentially leading to new treatments. #DrugDiscovery #Chemistry

Doraghi F¹ ; Serajian A² ; Karimian S³ ; Ghanbarlou M¹ ; Moradkhani F¹ ; Larijani B¹ ; Mahdavi M¹

Source: RSC Advances Published:2024

Abstract

1,3-Dipolar cycloaddition is one of the important chemical reactions between a 1,3-dipole and a dipolarophile to construct a five-membered heterocyclic compound. As an available α-amino acid reactant, l-proline is extensively used in 1,3-dipolar cycloaddition reactions. A diverse spectrum of bioactive spiro and fused N-heterocycles is obtained through this synthetic approach. In this review, we have described the use of l-proline in the synthesis of various spiro- and fused heterocyclic scaffolds. © 2024 The Royal Society of Chemistry.

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Mohammad Mahdavi (6)

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Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline

Style	Citing Format
MLA	Doraghi F, et al.. "Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline." RSC Advances, vol. 14, no. 12, 2024, pp. 8481-8501.
APA	Doraghi F, Serajian A, Karimian S, Ghanbarlou M, Moradkhani F, Larijani B, Mahdavi M (2024). Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline. RSC Advances, 14(12), 8481-8501.
Chicago	Doraghi F, Serajian A, Karimian S, Ghanbarlou M, Moradkhani F, Larijani B, Mahdavi M. "Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline." RSC Advances 14, no. 12 (2024): 8481-8501.
Harvard	Doraghi F et al. (2024) 'Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline', RSC Advances, 14(12), pp. 8481-8501.
Vancouver	Doraghi F, Serajian A, Karimian S, Ghanbarlou M, Moradkhani F, Larijani B, et al.. Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline. RSC Advances. 2024;14(12):8481-8501.
BibTex	@article{ author = {Doraghi F and Serajian A and Karimian S and Ghanbarlou M and Moradkhani F and Larijani B and Mahdavi M}, title = {Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline}, journal = {RSC Advances}, volume = {14}, number = {12}, pages = {8481-8501}, year = {2024} }
RIS	TY - JOUR AU - Doraghi F AU - Serajian A AU - Karimian S AU - Ghanbarlou M AU - Moradkhani F AU - Larijani B AU - Mahdavi M TI - Decarboxylative 1,3-Dipolar Cycloadditions of L-Proline JO - RSC Advances VL - 14 IS - 12 SP - 8481 EP - 8501 PY - 2024 ER -

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