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Disulfoton Publisher



Nasab MHF1, 2 ; Manavi MA1, 2 ; Baeeri M1, 2, 3
Authors
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Authors Affiliations
  1. 1. Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Toxicology and Pharmacology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023


Abstract

A pesticide called disulfoton is an organophosphate acetylcholinesterase inhibitor. Di-Syston is the brand name that Bayer CropScience produced. While the technical product used in vegetable fields is black and brownish with a sulfuric odor, disulfoton is a white oil in its pure form. The insecticide provides long-lasting control by acting as a cholinesterase inhibitor. Disulfoton was prohibited from being used in pesticides by the Environmental Protection Agency (EPA) in 2009, although the stock may still be sold until 2011. There aren’t any disulfoton-containing goods on the market right now. Like other organophosphorus insecticides, disulfoton is unstable in acidic conditions and degrades in alkaline conditions. Disulfoton insecticide manages insects that harm various agricultural and vegetable crops. An important feature of organophosphate pesticide poisoning is the inhibition of esterase, particularly acetylcholinesterase, which has a key physiological function. The digestive system quickly absorbs disulfoton after oral treatment. Disulfoton is unlikely to have genotoxic or reproductive effects on humans at exposure levels. © 2024 Elsevier Inc. All rights reserved.