Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms

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Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms Publisher

Karami Fath M¹ ; Babakhaniyan K² ; Anjomrooz M³ ; Jalalifar M⁴ ; Alizadeh SD⁴ ; Pourghasem Z⁵ ; Abbasi Oshagh P⁶ ; Azargoonjahromi A⁷ ; Almasi F⁸ ; Manzoor HZ⁹ ; Khalesi B¹⁰ ; Pourzardosht N¹¹ ; Khalili S¹² ; Payandeh Z¹³

Show Affiliations

1. Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, 1571914911, Iran
2. Department of Medical Surgical Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, 1996713883, Iran
3. Department of Radiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, 1411713135, Iran
4. Faculty of Medicine, Kerman University of Medical Sciences, Kerman, 7616914115, Iran
5. Department of Microbiology, Islamic Azad University of Lahijan, Gilan, 4416939515, Iran
6. Department of Biology, Faculty of Basic Sciences, Malayer University, Malayer, 6571995863, Iran
7. Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, 7417773539, Iran
8. Pharmaceutical Biotechnology Lab, Department of Microbial Biotechnology, School of Biology and Center of Excellence in Phylogeny of Living Organisms, College of Science, University of Tehran, Tehran, 1411734115, Iran
9. Experimental and Translational Medicine, University of Insubria, Via jean Henry Dunant 3, Varese, 21100, Italy
10. Department of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization, Karaj, 3197619751, Iran
11. Cellular and Molecular Research Center, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, 4193713111, Iran
12. Department of Biology Sciences, Shahid Rajaee Teacher Training University, Tehran, 1678815811, Iran
13. Department of Medical Biochemistry and Biophysics, Division Medical Inflammation Research, Karolinska Institute, Stockholm, SE-17177, Sweden

Source: Vaccines Published:2022

Abstract

Glioblastoma (GBM) is the most typical and aggressive form of primary brain tumor in adults, with a poor prognosis. Successful glioma treatment is hampered by ineffective medication distribution across the blood-brain barrier (BBB) and the emergence of drug resistance. Although a few FDA-approved multimodal treatments are available for glioblastoma, most patients still have poor prognoses. Targeting epigenetic variables, immunotherapy, gene therapy, and different vaccine- and peptide-based treatments are some innovative approaches to improve anti-glioma treatment efficacy. Following the identification of lymphatics in the central nervous system, immunotherapy offers a potential method with the potency to permeate the blood-brain barrier. This review will discuss the rationale, tactics, benefits, and drawbacks of current glioma therapy options in clinical and preclinical investigations. © 2022 by the authors.

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Style	Citing Format
MLA	Karami Fath M, et al.. "Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms." Vaccines, vol. 10, no. 9, 2022, pp. -.
APA	Karami Fath M, Babakhaniyan K, Anjomrooz M, Jalalifar M, Alizadeh SD, Pourghasem Z, Abbasi Oshagh P, Azargoonjahromi A, Almasi F, Manzoor HZ, Khalesi B, Pourzardosht N, Khalili S, Payandeh Z (2022). Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms. Vaccines, 10(9), -.
Chicago	Karami Fath M, Babakhaniyan K, Anjomrooz M, Jalalifar M, Alizadeh SD, Pourghasem Z, Abbasi Oshagh P, et al.. "Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms." Vaccines 10, no. 9 (2022): -.
Harvard	Karami Fath M et al. (2022) 'Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms', Vaccines, 10(9), pp. -.
Vancouver	Karami Fath M, Babakhaniyan K, Anjomrooz M, Jalalifar M, Alizadeh SD, Pourghasem Z, et al.. Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms. Vaccines. 2022;10(9):-.
BibTex	@article{ author = {Karami Fath M and Babakhaniyan K and Anjomrooz M and Jalalifar M and Alizadeh SD and Pourghasem Z and Abbasi Oshagh P and Azargoonjahromi A and Almasi F and Manzoor HZ and Khalesi B and Pourzardosht N and Khalili S and Payandeh Z}, title = {Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms}, journal = {Vaccines}, volume = {10}, number = {9}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Karami Fath M AU - Babakhaniyan K AU - Anjomrooz M AU - Jalalifar M AU - Alizadeh SD AU - Pourghasem Z AU - Abbasi Oshagh P AU - Azargoonjahromi A AU - Almasi F AU - Manzoor HZ AU - Khalesi B AU - Pourzardosht N AU - Khalili S AU - Payandeh Z TI - Recent Advances in Glioma Cancer Treatment: Conventional and Epigenetic Realms JO - Vaccines VL - 10 IS - 9 SP - EP - PY - 2022 ER -

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