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Clinical Cell Therapy Guidelines for Neurorestoration (Ianr/Canr 2017) Publisher Pubmed



Huang H1 ; Young W2 ; Chen L3 ; Feng S4 ; Zoubi ZMA5 ; Sharma HS6 ; Saberi H7 ; Moviglia GA8 ; He X9 ; Muresanu DF10 ; Sharma A11 ; Otom A12 ; Andrews RJ13 ; Alzoubi A14 Show All Authors
Authors
  1. Huang H1
  2. Young W2
  3. Chen L3
  4. Feng S4
  5. Zoubi ZMA5
  6. Sharma HS6
  7. Saberi H7
  8. Moviglia GA8
  9. He X9
  10. Muresanu DF10
  11. Sharma A11
  12. Otom A12
  13. Andrews RJ13
  14. Alzoubi A14
  15. Bryukhovetskiy AS15
  16. Chernykh ER16
  17. Domanskajanik K17
  18. Jafar E5
  19. Johnson WE18
  20. Li Y19
  21. Li D19
  22. Luan Z20
  23. Mao G1
  24. Shetty AK21
  25. Siniscalco D22
  26. Skaper S23
  27. Sun T24
  28. Wang Y25
  29. Wiklund L26
  30. Xue Q27
  31. You SW28
  32. Zheng Z29
  33. Dimitrijevic MR30
  34. Masri WSE31
  35. Sanberg PR32
  36. Xu Q33
  37. Luan G34
  38. Chopp M35
  39. Cho KS36
  40. Zhou XF37
  41. Wu P38
  42. Liu K39
  43. Mobasheri H40
  44. Ohtori S41
  45. Tanaka H42
  46. Han F43
  47. Feng Y44
  48. Zhang S45
  49. Lu Y46
  50. Zhang Z24
  51. Rao Y47
  52. Tang Z48
  53. Xi H49
  54. Wu L50
  55. Shen S51
  56. Xue M52
  57. Xiang G53
  58. Guo X54
  59. Yang X55
  60. Hao Y56
  61. Hu Y57
  62. Li J26
  63. Ao Q58
  64. Wang B59
  65. Zhang Z24
  66. Lu M61
  67. Li T62
Show Affiliations
Authors Affiliations
  1. 1. Institute of Neurorestoratology, General Hospital of Armed Police Forces, Beijing, China
  2. 2. W. M. Keck Center for Collaborative Neuroscience, Rutgers, State University of New Jersey, Piscataway, NJ, United States
  3. 3. Department of Neurosurgery, Tsinghua University Yuquan Hospital, Beijing, China
  4. 4. Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, China
  5. 5. Jordan Ortho and Spinal Centre, Al-Saif Medical Center, Amman, Jordan
  6. 6. Intensive Experimental CNS Injury and Repair, University Hospital, Uppsala University, Uppsala, Sweden
  7. 7. Department of Neurosurgery, Brain and Spinal Injury Research center, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Center of Research and Engineer of Tissues and Cellular Therapy, Maimonides University, Buenos Aires, Argentina
  9. 9. Department of Orthopaedics, Second Affiliated Hospital of Xi’an Jiaotong University, Xian, China
  10. 10. Department of Neurosciences “Iuliu Hatieganu, � University of Medicine and Pharmacy, Cluj-Napoca, Romania
  11. 11. Department of Neurosurgery, LTM Medical College, LTMG Hospital, Mumbai, Mumbai, India
  12. 12. Royal Rehabilitation Center, King Hussein Medical Centre-RJRC Amman, Jordan
  13. 13. Nanotechnology & Smart Systems, NASA Ames Research Center, Silicon Valley, CA, United States
  14. 14. The University of Illinois College of Medicine in Peoria, Peoria, IL, United States
  15. 15. NeuroVita Clinic of Interventional and Restorative Neurology and Therapy, Kashirskoye shosse, Moscow, Russian Federation
  16. 16. Lab of Cellular Immunotherapy, Institute of Fundamental and Clinical Immunology, Novosibirsk, Russian Federation
  17. 17. Stem Cell Bioengineering Unit, Mossakowski Medical Research Centre, Warsaw, Poland
  18. 18. Stem Cells and Regenerative Biology, Faculty of Medicine Dentistry and Life Sciences, University of Chester, Chester, United Kingdom
  19. 19. Spinal Repair Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, United Kingdom
  20. 20. Department of Pediatrics, Navy General Hospital of PLA, Beijing, China
  21. 21. Department of Molecular and Cellular Medicine, Institute for Regenerative Medicine, Texas A&M Health Science Center College of Medicine, College Station, TX, United States
  22. 22. Department of Experimental Medicine, University of Campania “Luigi Vanvitelli, � Naples, Italy
  23. 23. Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
  24. 24. Department of orthopedics, PLA Army General Hospital, Beijing, China
  25. 25. Department of Neurology, 148th Hospital, Zibo, Shandong, China
  26. 26. Unit of Neurology, Department of Pharmacology and Clinical Neuroscience, Umea University, Ostersund, Sweden
  27. 27. Department of Neurology, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, China
  28. 28. Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi’an, China
  29. 29. Department of Rehabilitation Medicine, The Central Hospital of Taian, Taian, Shandong, China
  30. 30. Baylor College of Medicine, Houston, TX, United States
  31. 31. Spinal Injuries Unit, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom
  32. 32. Center of Excellence for Aging & Brain Repair, Morsani College of Medicine, University of South Florida, Tampa, FL, United States
  33. 33. Institute of Neuroscience, Capital Medical University, Beijing, China
  34. 34. Department of Neurosurgery, Beijing Sanbo Brain Hospital, Capital Medical University, Beijing, China
  35. 35. Henry Ford Hospital, Henry Ford Health System, Neurology Research, Detroit, MI, United States
  36. 36. Department of Neurosurgery, Uijongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijongbu, South Korea
  37. 37. Division of Health Sciences, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia
  38. 38. Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, United States
  39. 39. Division of Life Science, The Hong Kong University of Science and Technology, Kowloon, Hong Kong
  40. 40. Biomaterials Research Center, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
  41. 41. Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
  42. 42. Department of Orthopaedic Surgery, Graduate School of Medicine, Osaka University, Osaka, Japan
  43. 43. Centre for Stem Cells and Regenerative Medicine, Liaocheng University/Liaocheng People’s Hospital, Liaocheng, Shandong, China
  44. 44. Department of Neurosurgery, Kunming General Hospital of Chengdu Military Command of Chinese PLA, Kunming, Yunnan, China
  45. 45. Department of Orthopedics, Changhai Hospital, The Second Military Medical University, Shanghai, China
  46. 46. Department of Neurosurgery, Chengde Dadu Hospital, Weichang, Hebei, China
  47. 47. Department of Spinal Surgery, Luoyang Orthopedic Hospital of Henan Province, Luoyang, Henan, China
  48. 48. Department of Neurology, Tongji Medical College of HUST, Tongji Hospital, Wuhan, China
  49. 49. Department of Neurology, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, China
  50. 50. Center of Rehabilitation, Beijing Xiaotangshan Rehabilitation Hospital, Beijing, China
  51. 51. Department of Rehabilitation, Weihai Municipal Hospital, Weihai, Shandong, China
  52. 52. Department of Neurorehabilitation, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
  53. 53. Brain Hospital of Hunan Province, Changsha, Hunan, China
  54. 54. Department of Neurology, PLA Army 266 Hospital, Chengde, Hebei, China
  55. 55. Department of Neurosurgery, The First Affiliated Hospital of Zhejiang University Medical College, Hangzhou, Zhejiang, China
  56. 56. Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China
  57. 57. Department of Orthopaedic and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong
  58. 58. Department of tissue engineering, China Medical University, Shenyang, Liaoning, China
  59. 59. Department of Traumatology, The Second Affiliated Hospital of Guangzhou Medical University, Haizhu District, Guangzhou, China
  60. 60. Department of Neurosurgery, First Affiliated Hospital of Chinese PLA General Hospital, Beijing, China
  61. 61. Department of Neurosurgery, Second Affiliated Hospital of Hunan Normal University (163 Hospital of PLA), Changsha, Hunan, China
  62. 62. Department of Neurology, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China

Source: Cell Transplantation Published:2018


Abstract

Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011. The IANR and the Chinese Association of Neurorestoratology (CANR) collaborated to propose the current version “Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)”. The IANR council board members and CANR committee members approved this proposal on September 1, 2016, and recommend it to clinical practitioners of cellular therapy. These guidelines include items of cell type nomenclature, cell quality control, minimal suggested cell doses, patient-informed consent, indications for undergoing cell therapy, contraindications for undergoing cell therapy, documentation of procedure and therapy, safety evaluation, efficacy evaluation, policy of repeated treatments, do not charge patients for unproven therapies, basic principles of cell therapy, and publishing responsibility. © 2018, © The Author(s) 2018.
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