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Halloysite Nanotubes in Biomedical Applications: Recent Approaches and Future Trends Publisher



Boraei SBA1 ; Eshghabadi F2 ; Hosseinpour R2 ; Zare Y1 ; Munir MT3 ; Rhee KY4
Authors
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Authors Affiliations
  1. 1. Biomaterials and Tissue Engineering Research Group, Department of Interdisciplinary Technologies, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran
  2. 2. Department of Life Sciences Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran
  3. 3. College of Engineering and Technology, American University of the Middle East, Egaila, 54200, Kuwait
  4. 4. Department of Mechanical Engineering (BK21 Four), College of Engineering, Kyung Hee University, Yongin, South Korea

Source: Applied Clay Science Published:2024


Abstract

In recent decades, nanomaterials have become an integral part of biomedical research. Halloysite nanotube (Hal) is one of the important nanomaterials, which has a key role in biomedical applications. Hal forms hydrogen bonds with biomaterials through siloxane and aluminol groups on the top of its surface. The wide range of Hal applications is attributed to its special properties, such as tubular structure, high porosity, excellent biocompatibility, good mechanical and thermal properties, high surface-to-volume ratio, and a high potential for controlled drug release. In this review, we summarize the main properties and characteristics of Hals and describe their biomedical applications in bone repair, wound healing, biosensors, drug carrier, and tissue engineering. Finally, we note the trend, future, and prospective applications of Hals in the biomedical field. © 2024 Elsevier B.V.
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