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A Review on the Phytochemistry, Pharmacology, and Therapeutic Effects of Rheum Ribes Publisher Pubmed



Keshavarzi Z1, 2 ; Shakeri F1, 2 ; Maghool F3 ; Jamialahmadi T4, 5 ; Johnston TP6 ; Sahebkar A7, 8, 9, 10
Authors
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Authors Affiliations
  1. 1. Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
  2. 2. Department of Physiology and Pharmacology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
  3. 3. Poursina Hakim Digestive Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran
  5. 5. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  6. 6. Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, Kansas City, MO, United States
  7. 7. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
  8. 8. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  9. 9. Polish Mother’s Memorial Hospital Research Institute (PMMHRI), Lodz, Poland
  10. 10. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Advances in Experimental Medicine and Biology Published:2021


Abstract

Herbal medications are typically used for the treatment of diverse diseases without significant adverse effects. The Rheum ribes (R. ribes), commonly called rhubarb, is a hardy perennial herb and is consumed all over the world. There is growing evidence of the therapeutic benefits of R. ribes. Extensive in vitro and in vivo investigations have shown that R. ribes reveals beneficial properties via different mechanisms. In the current article, various pharmacological and therapeutic effects of R. ribes have been reviewed. For this purpose, different online databases using keywords such as R. ribes, therapeutic effects, and pharmacological effects were searched until the end of December 2020. R. ribes has been suggested to be effective in the treatment of a wide range of disorders including stomachache, nausea and vomiting, hemorrhoids, and measles. Additionally, different studies have demonstrated that R. ribes possesses numerous pharmacological properties including anti-inflammatory, anticancer, antibacterial, and antiviral, and may also function as an expectorant. The present narrative review provides a detailed survey of scientific investigations regarding the pharmacological properties and therapeutic effects of R. ribes. © 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.
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