Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Effects of Herbal Medicines on Cancer Therapy-Induced Oral Mucositis: A Literature Review Publisher Pubmed

Summary: Research suggests herbal medicines reduce mouth sores from cancer treatment, offering a safe, natural relief option. #CancerCare #HerbalMedicine

Safarzadeh S1 ; Shirban F2 ; Bagherniya M3, 4, 5 ; Sathyapalan T6 ; Sahebkar A7, 8, 9, 10
Authors

Source: Phytotherapy Research Published:2022


Abstract

Cancer therapy-induced oral mucositis (OM) is one of the most troublesome morbidities after radio-chemotherapy. Age, nutritional status, tumor type, oral hygiene, and treatment method are the determinants for OM incidence. In addition, oxygen-free radicals can act as a trigger for an inflammatory milieu that causes OM. Based on the debilitating nature of OM, finding a safe and inexpensive agent with anti-inflammatory, anti-microbial, and antioxidative properties can be valuable for this situation. Considering the harmful effects of some chemical agents, herbal medicine has been suggested as a potential alternative owing to unique properties such as safety, availability and low cost. Many studies have illustrated several pharmacological properties of herbal medicines in recent years, such as anti-inflammatory, anti-microbial, and antioxidative activities, which are essential factors in the palliation of cancer therapy-induced OM. This review aimed to evaluate herbal medicines' effects on cancer therapy-induced OM. According to this comprehensive review, it is concluded that medicinal plants and phytochemicals can be used as practical agents in the palliation of cancer therapy-induced OM without any serious side effects. © 2021 John Wiley & Sons Ltd.
Related Docs
View other Related Docs
1. Investigating the Effect of Aloe Vera on the Prevention and Treatment of Radiotherapy‑Induced Oral Mucositis in Patients With Head‑And‑Neck Cancer, Journal of Research in Medical Sciences (2024)
2. The Effects of Nutraceuticals and Bioactive Natural Compounds on Chronic Periodontitis: A Clinical Review, Advances in Experimental Medicine and Biology (2021)
3. The Efficacy of Herbal Medicine in the Treatment of Recurrent Aphthous Stomatitis: A Systematic Review of Randomized Clinical Trials, Phytotherapy Research (2022)
Experts (# of related papers)
View all Related Experts
Mohammad Bagherniya (9)
Farinaz Shirban (3)
The Effects of Herbal Medicines on Cancer Therapy-Induced Oral Mucositis: A Literature Review
Other Related Docs
4. Evaluating the Safety and Efficacy of Silymarin in Β-Thalassemia Patients: A Review, Hemoglobin (2015)
5. The Effects of Phytochemicals and Herbal Bio-Active Compounds on Tumour Necrosis Factor-Α in Overweight and Obese Individuals: A Clinical Review, Inflammopharmacology (2022)
6. The Effects of Nutraceuticals and Herbal Medicine on Candida Albicans in Oral Candidiasis: A Comprehensive Review, Advances in Experimental Medicine and Biology (2021)
7. Protective Effects of Silymarin on Preventing Vancomycin Nephrotoxicity in Infectious Patients: A Randomized, Double-Blinded, Placebo-Controlled, Pilot Clinical Trial, Naunyn-Schmiedeberg's Archives of Pharmacology (2024)
8. Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review, Advances in Experimental Medicine and Biology (2021)
9. The Effect of Herbal Medicine and Natural Bioactive Compounds on Plasma Adiponectin: A Clinical Review, Advances in Experimental Medicine and Biology (2021)
10. Protective Effects of Curcumin in the Reproductive System: Anti-Toxic, Semen Cryopreservative, and Contraceptive Actions, Advances in Experimental Medicine and Biology (2021)
11. Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial, Complementary Therapies in Medicine (2020)
12. The Efficacy of Oral Hydrogel Containing Hyaluronic Acid, Polyvinylpyrrolidone, and Glycyrrhizin for Prevention and Treatment of Oral Mucositis Induced by Chemotherapy, Journal of Isfahan Medical School (2021)
13. Medicinal Plants and Bioactive Natural Products As Inhibitors of Nlrp3 Inflammasome, Phytotherapy Research (2021)
14. Antioxidant Effect of Ziziphus Vulgaris, Portulaca Oleracea, Berberisintegerima and Gundelia Tournefortti on Lipid Peroxidation, Hb Glycosylation and Red Blood Cell Hemolysis, Journal of Medicinal Plants (2011)
15. The Effects of Medicinal Plants and Bioactive Natural Compounds on Homocysteine, Molecules (2021)
16. Combined Therapy of Silymarin and Desferrioxamine in Patients With Β-Thalassemia Major: A Randomized Double-Blind Clinical Trial, Fundamental and Clinical Pharmacology (2009)
17. The Effects of Curcumin in the Treatment of Gingivitis: A Systematic Review of Clinical Trials, Advances in Experimental Medicine and Biology (2021)
18. An Overview of the Uses of Propolis for Oral Health, Advancements in Life Sciences (2023)
19. Preventive Effects of Achillea Millefolium, Rosa Damascena and Origanum Majorana Hydroalcoholic Extracts on Breast Cancer in Female Mice, Current Cancer Therapy Reviews (2023)
20. Curcumin Supplementation Prevents Cisplatin-Induced Nephrotoxicity: A Randomized, Double-Blinded, and Placebo-Controlled Trial, Research in Pharmaceutical Sciences (2023)