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Application of Systemic Inflammation Score for the Assessment of Contrast-Induced Acute Kidney Injury; a Review Publisher



Mirfendereski S1 ; Taghipour M2 ; Yadollahi F3 ; Taghavinejad H4 ; Ahmadnia M4
Authors
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Authors Affiliations
  1. 1. Department of Radiology, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Internal Medicine, School of Medicine Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, Iran
  3. 3. Departments of Medicine, Medical School, Shahrekord University of Medical Sciences, Shahrekord, Iran
  4. 4. Shahrekord University of Medical Sciences, Shahrekord, Iran

Source: Journal of Nephropathology Published:2024


Abstract

Contrast-related acute renal failure is a multifactorial condition that involves oxidative stress, inflammation, and direct tubular toxicity. Risk factors for contrast-induced nephropathy comprise pre-existing kidney dysfunction, diabetes mellitus, advanced age, congestive heart failure, hypotension, anemia, and volume depletion. Preventive measures include identifying high-risk patients and implementing preventive measures such as adequate hydration, minimizing contrast use, and avoiding using contrast media in patients with pre-existing renal dysfunction. The systemic inflammation score is a promising tool for predicting contrast-associated acute kidney injury (CA-AKI) in patients undergoing contrast-enhanced imaging procedures. Further studies are needed to validate the use of SIS in clinical practice and to better understand the underlying mechanisms of inflammation in (CA-AKI). © 2024 The Author(s);.
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