Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Mortality and Disability-Adjusted Life Years in North Africa and Middle East Attributed to Kidney Dysfunction: A Systematic Analysis for the Global Burden of Disease Study 2019 Publisher



Rashidi MM1, 2 ; Moghaddam SS1, 106 ; Azadnajafabad S1 ; Mohammadi E1, 3 ; Khalaji A1, 3 ; Malekpour MR1 ; Keykhaei M1, 4 ; Rezaei N1, 5 ; Esfahani Z1 ; Rezaei N1, 5 ; Mokdad AH104, 105 ; Murray CJL104, 105 ; Naghavi M104, 105 ; Larijani B5 Show All Authors
Authors
  1. Rashidi MM1, 2
  2. Moghaddam SS1, 106
  3. Azadnajafabad S1
  4. Mohammadi E1, 3
  5. Khalaji A1, 3
  6. Malekpour MR1
  7. Keykhaei M1, 4
  8. Rezaei N1, 5
  9. Esfahani Z1
  10. Rezaei N1, 5
  11. Mokdad AH104, 105
  12. Murray CJL104, 105
  13. Naghavi M104, 105
  14. Larijani B5
  15. Farzadfar F1, 5
  16. Abbasikangevari M1
  17. Abbasikangevari Z1, 2
  18. Elhafeez SA6
  19. Abdelsalam S7
  20. Abdoun M8
  21. Abugharbieh E9
  22. Ahmad A10
  23. Ahmed A11, 12
  24. Alazzam S13
  25. Alraddadi RM14
  26. Altammemi AB15, 16
  27. Dehkordi JA17, 18
  28. Behghadami MA19, 20
  29. Arabloo J21
  30. Athar M22, 23
  31. Athari SS24
  32. Babaei M25, 26
  33. Babamohamadi H27
  34. Baghcheghi N28
  35. Bagherieh S29
  36. Baradaran HR30, 31
  37. Bhagavathula AS32
  38. Bhojaraja VS33
  39. Hashemi MB34
  40. Campos LA35, 36
  41. Dehghan A37
  42. Elhadi M38
  43. Elhuneidi W39
  44. Fatehizadeh A40
  45. Feizkhah A41
  46. Ghadirian F42
  47. Gholami A43, 44
  48. Hamidi S45
  49. Hassankhani H46, 47
  50. Heidariforoozan M1, 48
  51. Hessami K49, 50
  52. Hezam K51, 52
  53. Hosseini MS53
  54. Hoveidamanesh S54
  55. Irilouzadian R48, 55
  56. Jahrami H56, 57
  57. Jamialahmadi T58, 59
  58. Jayapal SK60
  59. Karasneh RA61
  60. Khan MAB62, 63
  61. Khan YH64
  62. Khatatbeh MM61
  63. Kompani F65
  64. Koohestani HR66
  65. Kuddus M67
  66. Mahjoub S68, 69
  67. Mahmoodpoor A70
  68. Rad EM71
  69. Malik AA72, 73
  70. Mallhi TH64
  71. Mobayen M74
  72. Mohammadi F75
  73. Mohan S76, 77
  74. Momtazmanesh S1, 3
  75. Natto ZS78, 79
  76. Nejadghaderi SA1, 48
  77. Okatialiabad H80
  78. Rashedi S1, 81
  79. Rashidi A82
  80. Rashidi M83
  81. Mohamed Redwan EM84, 85
  82. Saad AMA86
  83. Sharifaskari FS87
  84. Sahebkar A88, 89
  85. Saki M90
  86. Samy AM91
  87. Shaker E1, 3
  88. Shetty JK92
  89. Shorofi SA93, 94
  90. Tabish M95
  91. Taherkhani A96
  92. Umair M97, 98
  93. Vahabi SM99
  94. Yazdanpanah F100, 101
  95. Yigit A102
  96. Zahir M103
  97. Zangiabadian M48
Show Affiliations
Authors Affiliations
  1. 1. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Epidemiology Department, Alexandria University, Alexandria, Egypt
  7. 7. Tropical Medicine Department, Tanta University, Tanta, Egypt
  8. 8. Department of Medicine, University of Setif Algeria, Setif, Algeria
  9. 9. Clinical Sciences Department, University of Sharjah, Sharjah, United Arab Emirates
  10. 10. Department of Medical Biochemistry, Shaqra University, Shaqra, Saudi Arabia
  11. 11. Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan
  12. 12. Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland
  13. 13. Department of Clinical Pharmacy, Jordan University of Science and Technology, Irbid, Jordan
  14. 14. Department of Community Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
  15. 15. Migration Health Division, International Organization for Migration, Amman, Jordan
  16. 16. Department of Family and Occupational Medicine, University of Debrecen, Debrecen, Hungary
  17. 17. Department of Applied Science and Technology, University of California Berkeley, Berkeley, CA, United States
  18. 18. Chemical Engineering Department, Tarbiat Modares University, Tehran, Iran
  19. 19. Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  20. 20. Department of Health Service Management, Iranian Center of Excellence in Health Management, Tabriz, Iran
  21. 21. Health Management and Economics Research Center, Iran University of Medical Sciences, Tehran, Iran
  22. 22. Department of Medical Genetics, Umm Al-Qura University, Makkah, Saudi Arabia
  23. 23. Science and Technology Unit, Umm Al-Qura University, Makkah, Saudi Arabia
  24. 24. Department of Immunology, Zanjan University of Medical Sciences, Zanjan, Iran
  25. 25. Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  26. 26. Department of Medicine, Stanford University, Palo Alto, CA, United States
  27. 27. Department of Nursing, Semnan University of Medical Sciences and Health Services, Semnan, Iran
  28. 28. Department of Nursing, Saveh University of Medical Sciences, Saveh, Iran
  29. 29. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  30. 30. Department of Epidemiology, Iran University of Medical Sciences, Tehran, Iran
  31. 31. Ageing Clinical and Experimental Research (ACER), University of Aberdeen, Aberdeen, United Kingdom
  32. 32. Department of Health, Human Performance and Recreation, University of Arkansas, Fayetteville, AR, United States
  33. 33. Department of Anatomy, Royal College of Surgeons in Ireland Medical University of Bahrain, Busaiteen, Bahrain
  34. 34. Urology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  35. 35. Center of Innovation, Technology and Education (CITE), Anhembi Morumbi University, Sao Jose dos Campos, Brazil
  36. 36. College of Health Sciences, Abu Dhabi University, Abu Dhabi, United Arab Emirates
  37. 37. Department of Epidemiology and Community Medicine, Non-Communicable Diseases Research Center (NCDRC), Fasa, Iran
  38. 38. Faculty of Medicine, University of Tripoli, Tripoli, Libya
  39. 39. Department of Basic Medical Sciences, University of Sharjah, Sharjah, United Arab Emirates
  40. 40. Department of Environmental Health Engineering, Isfahan University of Medical Sciences, Isfahan, Iran
  41. 41. Department of Social Medicine and Epidemiology, Guilan University of Medical Sciences, Rasht, Iran
  42. 42. Psychiatric Nursing and Management Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  43. 43. Department of Epidemiology and Biostatistics, Neyshabur University of Medical Sciences, Neyshabur, Iran
  44. 44. Non-Communicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran
  45. 45. School of Health and Environmental Studies, Hamdan Bin Mohammed Smart University, Dubai, United Arab Emirates
  46. 46. School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
  47. 47. Independent Consultant, Tabriz, Iran
  48. 48. School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  49. 49. Maternal Fetal Care Center, Harvard University, Boston, MA, United States
  50. 50. Maternal Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  51. 51. Department of Applied Microbiology, Taiz University, Taiz, Yemen
  52. 52. Department of Microbiology, Nankai University, Tianjin, China
  53. 53. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
  54. 54. Burn Research Center, Shahid Motahari Hospital, Tehran, Iran
  55. 55. Burn Research Center, Iran University of Medical Sciences, Tehran, Iran
  56. 56. College of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain
  57. 57. Ministry of Health, Manama, Bahrain
  58. 58. Department of Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
  59. 59. Department of Food Science and Technology, Islamic Azad University, Quchan, Iran
  60. 60. Centre of Studies and Research, Ministry of Health, Muscat, Oman
  61. 61. Department of Basic Medical Sciences, Yarmouk University, Irbid, Jordan
  62. 62. Family Medicine Department, United Arab Emirates University, Al Ain, United Arab Emirates
  63. 63. Primary Care Department, NHS North West London, London, United Kingdom
  64. 64. Department of Clinical Pharmacy, Jouf University, Sakaka, Saudi Arabia
  65. 65. Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  66. 66. Social Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran
  67. 67. Department of Biochemistry, University of Hail, Hail, Saudi Arabia
  68. 68. Cellular and Molecular Biology Research Center, Babol University of Medical Sciences, Babol, Iran
  69. 69. Department of Clinical Biochemistry, Babol University of Medical Sciences, Babol, Iran
  70. 70. Department of Anesthesiology and Critical Care, Tabriz University of Medical Sciences, Tabriz, Iran
  71. 71. Department of Pediatric Cardiology, Tehran University of Medical Sciences, Tehran, Iran
  72. 72. Rabigh Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
  73. 73. University Institute of Public Health, The University of Lahore, Lahore, Pakistan
  74. 74. Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
  75. 75. School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  76. 76. Substance Abuse and Toxicology Research Center, Jazan University, Jazan, Saudi Arabia
  77. 77. Center for Transdisciplinary Research, Saveetha Institute of Medical and Technical Science, Chennai, India
  78. 78. Department of Dental Public Health, King Abdulaziz University, Jeddah, Saudi Arabia
  79. 79. Department of Health Policy and Oral Epidemiology, Harvard University, Boston, MA, United States
  80. 80. Health Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
  81. 81. Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran
  82. 82. Rafsanjan University of Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
  83. 83. Department of Clinical Science, Islamic Azad University, Garmsar, Iran
  84. 84. Department Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
  85. 85. Department of Protein Research, Research and Academic Institution, Alexandria, Egypt
  86. 86. Cardiovascular Department, Zagazig University-Egypt, Zagazig, Egypt
  87. 87. Sharjah Institute of Medical Sciences, Sharjah, United Arab Emirates
  88. 88. Department of Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  89. 89. Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
  90. 90. Department of Microbiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  91. 91. Department of Entomology, Ain Shams University, Cairo, Egypt
  92. 92. Department of Biochemistry, Royal College of Surgeons, Ireland Medical University of Bahrain, Busaiteen, Bahrain
  93. 93. Department of Medical-Surgical Nursing, Mazandaran University of Medical Sciences, Sari, Iran
  94. 94. Department of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia
  95. 95. Department of Pharmacology, Shaqra University, Shaqra, Saudi Arabia
  96. 96. Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
  97. 97. Medical Genomics Research Department, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia
  98. 98. Department of Life Sciences, University of Management and Technology, Lahore, Pakistan
  99. 99. Faculty Of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  100. 100. Department of Pediatric Allergy and Immunology, Tabriz University of Medical Sciences, Tabriz, Iran
  101. 101. Department of Pediatric Allergy and Immunology, Tehran University of Medical Sciences, Tehran, Iran
  102. 102. Department of Health Management, Suleyman Demirel Universitesi (Suleyman Demirel University), Isparta, Turkey
  103. 103. Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  104. 104. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, United States
  105. 105. Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, United States
  106. 106. Kiel Institute for the World Economy, Kiel, Germany

Source: Clinical Kidney Journal Published:2024


Abstract

Background. The study aimed to estimate the attributable burden to kidney dysfunction as a metabolic risk factor in the North Africa and Middle East (NAME) region and its 21 countries in 1990-2019. Methods. The data used in this study were obtained from the Global Burden of Diseases (GBD) 2019 study, which provided estimated measures of deaths, disability-adjusted life years (DALYs), and other epidemiological indicators of burden. To provide a better insight into the differences in the level of social, cultural, and economic factors, the Socio-Demographic Index (SDI) was used. Results. In the NAME region in 2019, the number of deaths attributed to kidney dysfunction was 296 632 (95% uncertainty interval: 249 965-343 962), which was about 2.5 times higher than in the year 1990. Afghanistan, Egypt, and Saudi Arabia had the highest, and Kuwait, Turkey, and Iran (Islamic Republic of) had the lowest age-standardized rate of DALYs attributed to kidney dysfunction in the region in 2019. Kidney dysfunction was accounted as a risk factor for ischemic heart disease, chronic kidney disease, stroke, and peripheral artery disease with 150 471, 111 812, 34 068, and 281 attributable deaths, respectively, in 2019 in the region. In 2019, both low-SDI and high-SDI countries in the region experienced higher burdens associated with kidney dysfunction compared to other countries. Conclusions. Kidney dysfunction increases the risk of cardiovascular diseases burden and accounted for more deaths attributable to cardiovascular diseases than chronic kidney disease in the region in 2019. Hence, policymakers in the NAME region should prioritize kidney disease prevention and control, recognizing that neglecting its impact on other diseases is a key limitation in its management. © The Author(s) 2023. Published by Oxford University Press on behalf of the ERA. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Other Related Docs
13. Prevalence and Clinical Findings of Biopsy-Proven Glomerulonephritidis in Iran., Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2007)
41. A Six-Year Survey of the Spectrum of Renal Disorders on Native Kidney Biopsy Results in Central Iran and a Review of Literature, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2018)
50. Comparison of the Performance of the Updated Schwartz, Combined Schwartz and the Grubb Glomerular Filtration Rate Equations in a General Pediatric Population., Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (2014)