Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Relationship Between Dietary Inflammatory Index and Psychosomatic Complaints Profiles: Results From Sepahan Cross-Sectional Study Publisher



Haghighatdoost F1, 2, 3 ; Feizi A3, 4, 5 ; Esmaillzadeh A6 ; Feinlebisset C7 ; Hassanzadeh Keshteli A5, 8 ; Roohafza H9 ; Afshar H3 ; Adibi P8
Authors
Show Affiliations
Authors Affiliations
  1. 1. Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  6. 6. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. University of Adelaide, Discipline of Medicine and National Health and Medical Research Council, Centre of Research Excellence of Translating Nutritional Science to Good Health, Adelaide, Australia
  8. 8. Department of Medicine, University of Alberta, Edmonton, Canada
  9. 9. Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Source: BioPsychoSocial Medicine Published:2019


Abstract

Background: Although the dietary inflammatory index (DII) has been evaluated in relation to psychological disorders risk, the association between DII and psychosomatic complaints is unclear. This study aimed to determine the association between DII, as a proxy measure of the inflammatory potential of the diet, and psychosomatic complaints. Methods: This cross-sectional study included 2818 people from the general population, aged 19 to 69 years, of Isfahan province in Iran. Dietary intake was assessed using a validated dish-based food-frequency questionnaire. Psychosomatic complaints were assessed using a self-administered validated Persian questionnaire. Twenty-seven nutrients or foods were included in the calculation of DII. Each of them received a score based on their inflammatory ability, thus, a higher DII score indicated a more pro-inflammatory diet. The risk of being in the top median of a psychosomatic complaints profile across the tertiles of DII was assessed using logistic regression. Results: Four psychosomatic complaints profiles (psychological, gastrointestinal, neuro-skeletal and pharyngeal- respiratory) were identified. After controlling for potential confounders, individuals in the top tertile of DII had higher odds for experiencing high somatic complaints scores for the psychological (odds ratio (OR) = 1.44, 95% confidence interval (CI): 1.10, 1.89; P trend = 0.009), gastrointestinal (OR = 1.22, 95% CI: 0.99, 1.75; P = 0.058) or neuro-skeletal (OR = 1.56, 95% CI: 1.10, 2.22; P = 0.013) profile. The association for pharyngeal-respiratory complaints did not remain significant after adjustment for stressful life events, medical condition, and anti-psychotropic medicine use. Conclusion: The significant positive link between DII and the various psychosomatic complaints profiles suggests that a diet with anti-inflammatory potential might be favourably related to psychosomatic complaints. Further studies, particularly clinical trials and longitudinal studies, are warranted to investigate the inflammatory potential of diet in relation to psychosomatic complaints. © 2019 The Author(s).
Related Docs
View other Related Docs
1. Association Between the Dietary Inflammatory Index and Common Mental Health Disorders Profile Scores, Clinical Nutrition (2019)
2. The Mind (Mediterranean-Dash Diet Intervention for Neurodegenerative Delay) and Mediterranean Diets Are Differently Associated With Psychosomatic Complaints Profile in Adults: Results From Sepahan Cross-Sectional Study, Mediterranean Journal of Nutrition and Metabolism (2020)
3. Association Between Dietary Inflammatory Index and Psychological Profile in Adults, Clinical Nutrition (2019)
4. Empirically Derived Food-Based Dietary Inflammatory Index Is Associated With Increased Risk of Psychological Disorders in Women, Nutritional Neuroscience (2021)
5. Breakfast Skipping Alone and in Interaction With Inflammatory Based Quality of Diet Increases the Risk of Higher Scores of Psychological Problems Profile in a Large Sample of Iranian Adults, Journal of Nutritional Science (2021)
6. Dietary Patterns in Relation With Psychosomatic Complaints Profile: Results From Sepahan Study Among a Large Sample of General Adults, Nutritional Neuroscience (2020)
7. Is There a Link Between the Inflammatory Potential of a Diet and Mental Health Among Patients With Migraine? Findings From a Cross-Sectional Survey, Nutritional Neuroscience (2024)
8. Association Between Inflammatory Potential of the Diet and Ulcerative Colitis: A Case-Control Study, Frontiers in Nutrition (2021)
Experts (# of related papers)
View all Related Experts
Peyman Adibi (100)
Awat Feizi (60)
Other Related Docs
9. The Association Between the Dietary Inflammatory Index and Multiple Myeloma: A Case–Control Study, Scientific Reports (2025)
10. Adherence to the Pro-Inflammatory Diet in Relation to Prevalence of Irritable Bowel Syndrome, Nutrition Journal (2019)
11. Somatic Complaints Are Significantly Associated With Chronic Uninvestigated Dyspepsia and Its Symptoms: A Large Cross-Sectional Population Based Study, Journal of Neurogastroenterology and Motility (2017)
12. The Association of Dietary Inflammatory Index and Cognitive Function in Iranian Elders, Recent Advances in Food, Nutrition and Agriculture (2024)
13. Association Between Food-Based Dietary Inflammatory Potential and Ulcerative Colitis: A Case–Control Study, Scientific Reports (2023)
14. Dietary Inflammatory Index and Risk of Multiple Sclerosis: Findings From a Large Population-Based Incident Case–Control Study, Clinical Nutrition (2020)
15. Empirically Derived Food-Based Inflammatory Potential of the Diet, Irritable Bowel Syndrome, and Its Severity, Nutrition (2019)
16. Dietary Inflammatory Index and Its Association With the Risk of Cardiovascular Diseases, Metabolic Syndrome, and Mortality: A Systematic Review and Meta-Analysis, Hormone and Metabolic Research (2018)
17. The Association Between the Dietary Inflammatory Index and Glioma: A Case-Control Study, Clinical Nutrition (2020)
18. Association Between Dietary Inflammatory Index Scores and Diabetes Sensorimotor Polyneuropathy in Patients With Type 2 Diabetes Mellitus: A Case-Control Study, Evidence-based Complementary and Alternative Medicine (2022)
19. Consumption of Dietary Fiber in Relation to Psychological Disorders in Adults, Frontiers in Psychiatry (2021)
20. Inflammatory Potential of Diet and Odds of Lung Cancer: A Case-Control Study, Nutrition and Cancer (2022)
21. Associations Between Potential Inflammatory Properties of the Diet and Frequency, Duration, and Severity of Migraine Headaches: A Cross-Sectional Study, Scientific Reports (2022)
22. The Relationship Between Functional Constipation and Major Dietary Patterns in Iranian Adults: Findings From the Large Cross-Sectional Population-Based Sepahan Study, Preventive Nutrition and Food Science (2021)
23. Dietary Inflammatory Index and Dietary Energy Density Are Associated With Menopausal Symptoms in Postmenopausal Women: A Cross-Sectional Study, Menopause (2020)
24. Association Between the Dietary Inflammatory Index and Obesity in Otherwise Healthy Adults: Role of Age and Sex, International Journal of Clinical Practice (2021)
25. Association Between Inflammatory Potential of Diet and Markers of Malnutrition in Haemodialysis Patients, British Journal of Nutrition (2023)
26. The Association Between Dietary Inflammatory Index With Risk Rheumatoid Arthritis: A Case-Control Study, Prostaglandins and Other Lipid Mediators (2024)
27. Inflammatory Potential of the Diet and Risk of Sarcopenia and Its Components, Nutrition Journal (2020)
28. Glycemic Index, Glycemic Load, and Common Psychological Disorders, American Journal of Clinical Nutrition (2016)
29. Association of Dietary Inflammatory Potential (Dip) and Endothelial Function Biomarkers Among Females, Nutrition and Food Science (2022)
30. The Association Between Dietary Inflammatory Potential and Gastric Cancer: A Case Control Study, Nutrition and Cancer (2022)
31. Empirically Derived Dietary Patterns in Relation to Psychological Disorders, Public Health Nutrition (2016)
32. Psychological Distress, Perceived Stress and Nocebo Effect (Multifood Adverse Reaction) in Irritable Bowel Syndrome Patients, Journal of Education and Health Promotion (2023)
33. The Relationship Between Linoleic Acid Intake and Psychological Disorders in Adults, Frontiers in Nutrition (2022)
34. The Association of the Prime Diet Quality Score (Pdqs) With Depression and Anxiety Symptoms: The Isfahan Functional Disorders (Isfun) Cohort Study, Nutritional Neuroscience (2025)
35. Association of Dietary Phytochemical Index and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2019)
36. Demographic and Life Styles Determinants of Somatic Complaints’ Structures: A Cross-Sectional Study on a Large Sample of Iranian Adults Using Factor Mixture Model, International Journal of Preventive Medicine (2017)
37. Red and White Meat Intake in Relation to Mental Disorders in Iranian Adults, Frontiers in Nutrition (2021)
38. Association Between the Dietary Inflammatory Index and Markers of Endothelial and Systemic Inflammation in Hemodialysis Patients, Frontiers in Nutrition (2023)
39. Evaluation of the Relationship Between Major Dietary Patterns and Uninvestigated Reflux Among Iranian Adults, Nutrition (2016)
40. The Association Between Dietary Inflammatory Index With Some Cardio-Metabolic Risk Indices Among the Patients With Type 2 Diabetes From Hoveyzeh Cohort Study: A Cross-Sectional Study, BMC Endocrine Disorders (2024)
41. Dietary Glycemic Index and Glycemic Load in Relation to General Obesity and Central Adiposity Among Adults, Clinical Nutrition (2019)
42. The Relationship Between Fruit and Vegetable Intake With Functional Dyspepsia in Adults, Neurogastroenterology and Motility (2021)
43. Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides and Polyols Diet Is Associated With Increased Risk of Uninvestigated Chronic Dyspepsia and Its Symptoms in Adults, Minerva Gastroenterology (2023)
44. Adherence to the Vegetarian Diet May Increase the Risk of Depression: A Systematic Review and Meta-Analysis of Observational Studies, Nutrition Reviews (2022)
45. Association Between Dietary Inflammatory Index and Phase Angle in University Employees: A Cross-Sectional Study, Scientific Reports (2024)
46. Healthy Eating Index and Cardiovascular Risk Factors Among Iranians, Journal of the American College of Nutrition (2013)
47. Dietary Intake of Branched-Chain Amino Acids in Relation to Depression, Anxiety and Psychological Distress, Nutrition Journal (2021)
48. Elevated Risk of Possible Sarcopenia and Weak Muscle Strength With Higher Dietary Inflammatory Index in Iranian Breast Cancer Survivors: A Cross-Sectional Study, BMC Nutrition (2025)
49. Adherence to the Dash Diet in Relation to Psychological Profile of Iranian Adults, European Journal of Nutrition (2017)
50. The Role of Dietary Inflammation in the Risk of Osteoporosis in Iranian Postmenopausal Women: A Case-Control Study, Scientific Reports (2025)