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Overview on the Infections Related to Rare Candida Species Publisher



Kumar S1 ; Kumar A2 ; Roudbary M3 ; Mohammadi R4 ; Cernakova L5 ; Rodrigues CF6, 7, 8
Authors
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Authors Affiliations
  1. 1. Faculty of Biosciences, Institute of Biosciences and Technology, Shri Ramswaroop Memorial University, Uttar Pradesh, Barabanki, 225003, India
  2. 2. Department of Biotechnology, National Institute of Technology, Chhattisgarh, Raipur, 492010, India
  3. 3. Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, 1449614535, Iran
  4. 4. Department of Medical Parasitology and Mycology, Infectious Diseases and Tropical Medicine Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 8174673461, Iran
  5. 5. Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovicova 6, Bratislava, 842 15, Slovakia
  6. 6. TOXRUN—Toxicology Research Unit, CESPU—Cooperativa de Ensino Superior Politecnico e Universitario, Gandra PRD, 4585-116, Portugal
  7. 7. LEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, Porto, 4200-465, Portugal
  8. 8. ALiCE—Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, Porto, 4200-465, Portugal

Source: Pathogens Published:2022


Abstract

Atypical Candida spp. infections are rising, mostly due to the increasing numbers of immunocompromised patients. The most common Candida spp. is still Candida albicans; however, in the last decades, there has been an increase in non-Candida albicans Candida species infections (e.g., Candida glabrata, Candida parapsilosis, and Candida tropicalis). Furthermore, in the last 10 years, the reports on uncommon yeasts, such as Candida lusitaniae, Candida intermedia, or Candida norvegensis, have also worryingly increased. This review summarizes the information, mostly related to the last decade, regarding the infections, diagnosis, treatment, and resistance of these uncommon Candida species. In general, there has been an increase in the number of articles associated with the incidence of these species. Additionally, in several cases, there was a suggestive antifungal resistance, particularly with azoles, which is troublesome for therapeutic success. © 2022 by the authors.
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