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Paediatric Metabolic Syndrome and Associated Anthropometric Indices: The Caspian Study Publisher Pubmed



Kelishadi R1, 5 ; Ardalan G2 ; Gheiratmand R2 ; Adeli K3 ; Delavari A2 ; Majdzadeh R4
Authors
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Authors Affiliations
  1. 1. Preventive Paediatric Cardiology Department, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Clinical Biochemistry, Hospital for Sick Children, University of Toronto, Toronto, Ont., Canada
  4. 4. School of Public Health, Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Preventive Paediatric Cardiology Department, Isfahan Cardiovascular Research Centre (WHO Collaborating Centre in EMR), Isfahan University of Medical Sciences, Isfahan, PO Box 81465-1148, Iran

Source: Acta Paediatrica, International Journal of Paediatrics Published:2006


Abstract

Aim: To determine the prevalence of paediatric metabolic syndrome (MetS) and its best predictive anthropometric index. Methods: This national study was conducted among 4811 students (2248 boys and 2563 girls) aged 6-18 y. This is the first study of its kind in Iran and, to our knowledge, in Asia as well. Two definitions were used for the MetS: type A was defined based on criteria analogous to ATP III, and type B was defined according to the cut-offs obtained from NHANES III. Both types A and B define high fasting blood sugar as > 100 mg/dl and systolic/diastolic blood pressure as > 90th percentile. Results: The mean (SD) age of students studied was 12.07 ± 3.2 y. MetS type A was seven times more prevalent than type B (14% vs 2%, respectively, p < 0.0001), and had no significant gender difference. The most frequent components of both definitions of the MetS were low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG). Waist circumference (WC) and waist-to-hip ratio (WHR) had the strongest and weakest associations, respectively, with the MetS. Conclusion: Establishment of a uniform set of criteria for the MetS in children is needed. Routine WC measurement in the paediatric population may be clinically useful. © 2006 Taylor & Francis.
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