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Association of Anthropometric Indices With Cardiovascular Disease Risk Factors Among Children and Adolescents: Caspian Study Publisher Pubmed



Kelishadi R1 ; Gheiratmand R2 ; Ardalan G3 ; Adeli K4 ; Mehdi Gouya M5 ; Mohammad Razaghi E6 ; Majdzadeh R7 ; Delavari A8 ; Shariatinejad K9 ; Motaghian M2 ; Heshmat R7 ; Heidarzadeh A10 ; Barekati H6 ; Sadat Mahmoudarabi M6 Show All Authors
Authors
  1. Kelishadi R1
  2. Gheiratmand R2
  3. Ardalan G3
  4. Adeli K4
  5. Mehdi Gouya M5
  6. Mohammad Razaghi E6
  7. Majdzadeh R7
  8. Delavari A8
  9. Shariatinejad K9
  10. Motaghian M2
  11. Heshmat R7
  12. Heidarzadeh A10
  13. Barekati H6
  14. Sadat Mahmoudarabi M6
  15. Mehdi Riazi M6
Show Affiliations
Authors Affiliations
  1. 1. Preventive Pediatric Cardiology Department, Isfahan Cardiovascular Research Center (WHO-Collaborating Center in EMR), Isfahan University of Medical Sciences, Isfahan, P.O. Box 81465-1148, Iran
  2. 2. Bureau of Health, Iranian Ministry of Education, Iran
  3. 3. School Health Office, Iranian Ministry of Health, Iran
  4. 4. Clinical Biochemistry, Hospital for Sick Children, University of Toronto, Toronto, Ont., Canada
  5. 5. Center for Disease Control, Iranian Ministry of Health, Iran
  6. 6. Bureau of Youth, School Health, Iranian Ministry of Health, Iran
  7. 7. School of Public Health, Institute of Public Health Research, Tehran University of Medical Sciences, Iran
  8. 8. Non-communicable Disease Department, Center for Disease Control, Iranian Ministry of Health, Iran
  9. 9. Isfahan University of Medical Sciences, Iran
  10. 10. School of Medicine, Guilan University of Medical Sciences, Iran

Source: International Journal of Cardiology Published:2007


Abstract

Background: For the first time in Iran, and to the best of our knowledge in Asia, we assessed the anthropometric indices most closely correlated to cardiovascular disease (CVD) risk factors in a large nationally representative sample of children and adolescents to be used as a simple tool for identifying those at risk. Methods: This multi-center study was performed among a representative sample of 4811 school students (2248 boys and 2563 girls) aged 6-18 years, as part of the baseline survey of a national surveillance system. Anthropometric indices and CVD risk factors were measured using standard protocols, and their correlation was analyzed by using Receiver Operator Characteristic (ROC) curves and partial correlation. Results: The most prevalent CVD risk factors were low HDL-C (28%), followed by hypertriglyceridemia (20.1%), and overweight (17%). The ROC analyses showed that among boys, all anthropometric indices had the same association with CVD risk factors in 6-9.9-year-age group, while in the 10-13.9 and 14-18-year-age groups, respectively waist circumference (WC) and body mass index (BMI) were the best in distinguishing CVD risk factors. Among girls, these indices were respectively BMI and waist to stature ratio (WSR); WC and WSR; and WC. In the partial correlation analysis, in boys, the highest coefficient was found for BMI; BMI and WC; and for WC and WSR; in girls, these indices were BMI; WC and WSR; and BMI respectively. Conclusions: In the present study, BMI, WC and WSR were the most appropriate in predicting CVD risk factors. It may be clinically useful in the pediatric population to routinely measure WC and WSR in addition to BMI as a screening tool to identify high-risk youth. © 2006 Elsevier Ireland Ltd. All rights reserved.
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