Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
The Role of Gut Microbiota in Human Metabolism and Inflammatory Diseases: A Focus on Elderly Individuals Publisher



Khaledi M1, 2 ; Poureslamfar B3 ; Alsaab HO4 ; Tafaghodi S5 ; Hjazi A6 ; Singh R7 ; Alawadi AH8 ; Alsaalamy A9 ; Qasim QA10 ; Sameni F1
Authors

Source: Annals of Microbiology Published:2024


Abstract

Background: The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by a different abundance of bacteria in several age groups. Main body: Gut microbiota dysbiosis is associated with aging, antibiotic exposure, underlying diseases, infections, hormonal variations, circadian rhythm, and malnutrition, either singularly or in combination. The appropriate use of prebiotics and probiotics may be able to prevent or reduce this disruption. Conclusion: The current review focuses on the gut microbiota composition across the life cycle, factors affecting gut microbiota changes with aging, and interventions to modulate gut microbiota. © 2023, The Author(s).
Related Docs
View other Related Docs
1. Prebiotics and Probiotics and Parkinson's Disease, Treatments, Nutraceuticals, Supplements, and Herbal Medicine in Neurological Disorders (2023)
2. Effects of Probiotic Supplementation in Patients With Type 2 Diabetes: Systematic Review and Meta-Analysis, Nutrition Reviews (2016)
3. The Effects of 6 Mo of Supplementation With Probiotics and Synbiotics on Gut Microbiota in the Adults With Prediabetes: A Double Blind Randomized Clinical Trial, Nutrition (2020)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (3)
Mahin Hashemipour (2)
Other Related Docs
4. A Randomized Triple-Masked Controlled Trial on the Effects of Synbiotics on Inflammation Markers in Overweight Children, Jornal de Pediatria (2014)
5. Chronic Low-Grade Inflammation: Etiology and Its Effects, Journal of Isfahan Medical School (2016)
6. Microbiomes and Pediatric Onset Multiple Sclerosis (Ms): A Systematic Review, AIMS Neuroscience (2023)
7. Using Metabolomics to Investigate the Relationship Between the Metabolomic Profile of the Intestinal Microbiota Derivatives and Mental Disorders in Inflammatory Bowel Diseases: A Narrative Review, Research in Pharmaceutical Sciences (2025)
8. Effects of Probiotic Supplementation on Anthropometric and Metabolic Characteristics in Adults With Metabolic Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, Clinical Nutrition (2021)
9. Effect of Probiotic Consumption on Immune Response in Athletes: A Meta-Analysis, International Journal of Sports Medicine (2021)
10. The Dysbiosis Signature of Fusobacterium Nucleatum in Colorectal Cancer-Cause or Consequences? a Systematic Review, Cancer Cell International (2021)
11. The Prevalence of Adherent-Invasive Escherichia Coli and Its Association With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis, Frontiers in Medicine (2021)
12. The Potential Preventive Effect of Probiotics, Prebiotics, and Synbiotics on Cardiovascular Risk Factors Through Modulation of Gut Microbiota: A Review, Food Science and Nutrition (2024)
13. Synbiotic Containing Bacillus Coagulans and Fructo-Oligosaccharides for Functional Abdominal Pain in Children, Gastroenterology and Hepatology from Bed to Bench (2015)
14. Psychological Stress and Gut Microbiota Composition: A Systematic Review of Human Studies, Neuropsychobiology (2023)
15. A Synbiotic Mixture Ameliorates Depressive Behavior Induced by Dexamethasone or Water Avoidance Stress in a Mouse Model; [Fare Modelinde Deksametazon Ile Induklenen Depresif Davranisi Veya Sudan Kacinma Stresini Iyilestiren Sinbiyotik Bir Karisim], Turkish Journal of Pharmaceutical Sciences (2021)
16. The Effects of Probiotics on Body Weight and Biomarkers of Animal, Pakistan Journal of Nutrition (2013)
17. Gut Microbiota Dysbiosis: A Neglected Risk Factor for Male and Female Fertility, Cellular Microbiology (2024)
18. The Effects of Synbiotic Supplementation on Some Cardio-Metabolic Risk Factors in Overweight and Obese Children: A Randomized Triple-Masked Controlled Trial, International Journal of Food Sciences and Nutrition (2013)
19. Probiotics As a Novel Treatment for Non-Alcoholic Fatty Liver Disease; a Systematic Review on the Current Evidences, Hepatitis Monthly (2013)
20. Potential Mechanisms Linking Probiotics to Diabetes: A Narrative Review of the Literature; [Mecanismos Potenciais Ligando Probioticos a Diabetes: Uma Revisao Narrativa Da Literatura], Sao Paulo Medical Journal (2017)