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Chronic Low-Grade Inflammation: Etiology and Its Effects



Asgharzadeh F1 ; Rouzbahani R2 ; Khazaei M3
Authors
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Authors Affiliations
  1. 1. Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
  2. 2. Department of Community Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Neurogenic Inflammation Research Centre, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Journal of Isfahan Medical School Published:2016

Abstract

Chronic low-grade inflammation is a Para-clinical finding in several diseases including obesity, diabetes, nervous diseases and etc. Numerous studies have been done to determine the causes and effects of low-grade inflammation on the body. Today, chronic low-grade inflammation is considered in pathogenesis of these diseases. Chronic inflammation is reflected by increased circulating levels of gram-negative bacterial endotoxin lipopolysaccharide (LPS) which is associated by high level of inflammatory markers. Numerous factors can be involved in induction and progression of low-grade inflammation which lead to some consequences on different parts of body. In this review, we aimed to discuss about the causes and consequences of low-grade inflammation. © 2016, Isfahan University of Medical Sciences(IUMS). All rights reserved.
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