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Synthesis and Pharmacological Properties of Polysubstituted 2-Amino-4H-Pyran-3-Carbonitrile Derivatives Publisher Pubmed



Tashrifi Z1 ; Mohammadikhanaposhtani M2 ; Hamedifar H3, 4 ; Larijani B5 ; Ansari S3, 4 ; Mahdavi M5
Authors
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Authors Affiliations
  1. 1. Department of Chemistry, University of Guilan, PO Box 41335-1914, Rasht, Iran
  2. 2. Faculty of Fouman, College of Engineering, University of Tehran, Fuman, Iran
  3. 3. CinnaGen Medical Biotechnology Research Center, Alborz University of Medical Sciences, Karaj, Iran
  4. 4. CinnaGen Research and Production Co, Karaj, Alborz, Iran
  5. 5. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Molecular Diversity Published:2020


Abstract

Abstract: 2-Amino-3-cyano-4H-chromenes are structural core motifs that received increasing attention in the last years due to their interesting potential pharmacological properties. In this review, the synthetic methods for these compounds are classified based on the type of catalyst in the pertinent reactions. In addition, the wide range of pharmacological properties of these compounds is covered in a separate section. Graphic Abstract: [Figure not available: see fulltext.]. © 2019, Springer Nature Switzerland AG.