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Synthesis and Pharmacological Properties of Polysubstituted 2-Amino-4H-Pyran-3-Carbonitrile Derivatives Publisher Pubmed



Tashrifi Z1 ; Mohammadikhanaposhtani M2 ; Hamedifar H3, 4 ; Larijani B5 ; Ansari S3, 4 ; Mahdavi M5
Authors

Source: Molecular Diversity Published:2020


Abstract

Abstract: 2-Amino-3-cyano-4H-chromenes are structural core motifs that received increasing attention in the last years due to their interesting potential pharmacological properties. In this review, the synthetic methods for these compounds are classified based on the type of catalyst in the pertinent reactions. In addition, the wide range of pharmacological properties of these compounds is covered in a separate section. Graphic Abstract: [Figure not available: see fulltext.]. © 2019, Springer Nature Switzerland AG.