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Sars-Cov-2 Omicron Variant: Why Global Communities Should Take It Seriously? Publisher Pubmed



Rahmani S1, 2 ; Rezaei N2, 3, 4
Authors
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Authors Affiliations
  1. 1. Department of Medical Virology, Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Division of Medical Research, Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Division of Immunology, Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Immunity# Inflammation and Disease Published:2022


Abstract

Introduction: In November 26th, 2021 a new strain of SARS-CoV-2 was designated by the World Health Organization as a variant of concern and named Omicron. The news broadcasted a global wave of panic and anxiety while many, like 2 years ago, were making themselves ready for the holiday season. After almost a month of its designation, countries from all 6 continents have been reported Omicron from their genomic sequences. This triggered an international alarm about a new era in the Covid-19 pandemic, where despite the vast amount of vaccinations, a surge in new cases and hospitalizations are reported from all over the world. Methods: Scientific literature published from November 26, 2021 to March 21, 2022 have been searched and retrieved by using “SARS-COV-2”, “Omicron”, “B.1.1.529”, “Covid-19”, and “global community” keywords from “PubMed”, Web o “Google Scholar”, and “MedRxiv” databases. Results: Omicron have been evolved to spread faster than previous variants of concern, but it infects people lesser than other variants, Delta for example. Omicron can also escape vaccine-induced immunity more than previous SARS-CoV-2 variants. Discussion: Despite possible lower lethal risks than previous strains, Omicron may provide populations with a higher community transmission and a higher hospitalization load, which potentially overwhelm already exhausted health care systems. Therefore, we need to get used to the “New Normal” and maintain health recommendations to help decrease spreading of the virus and buy more time for the scientists to dive deeper into potential ways of tackling Covid-19, more than ever. © 2022 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.
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