Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share this content! By

Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer Publisher

Banstola A¹ ; Emami F² ; Jeong JH³ ; Yook S¹

Source: Macromolecular Research Published:2018

Abstract

Pancreatic cancer is an extremely heterogeneous, malignant disease with a complicated tumor microenvironment and a dismal prognosis. Extensive stroma surrounding the cancer and the sequestering of chemotherapeutic agents play dominant roles in tumor growth and metastasis and in suppressing the delivery of cytotoxic drugs to tumor cells. Currently, nanoscience is in the forefront of developments aimed at devising novel techniques to treat tumors. Gold nanoparticles (GNPs) are often used as potential imaging and therapeutic agents for cancers, since they offer: (1) Passive targeting because of better permeation and retention effects, (2) photothermal effects caused by efficient light-to-heat conversion, and (3) the potential to use simple gold-thiol bioconjugation chemistry to conjugate desired molecules for targeted drug delivery. Together, these benefits can increase the therapeutic success of GNPs when used in combination with conventional treatment strategies, such as surgery, chemotherapy, or radiotherapy. In this review, we discuss current trends in GNP research in the field of pancreatic cancer theranostics. © 2018, The Polymer Society of Korea and Springer Nature B.V.

Related Docs

View other Related Docs

1. An Overview of Biomedical Applications for Gold Nanoparticles Against Lung Cancer, Journal of Drug Delivery Science and Technology (2023)

2. Radiofrequency Electric Field Hyperthermia With Gold Nanostructures: Role of Particle Shape and Surface Chemistry, Artificial Cells# Nanomedicine and Biotechnology (2018)

3. A Nanotechnology-Based Strategy to Increase the Efficiency of Cancer Diagnosis and Therapy: Folate-Conjugated Gold Nanoparticles, Current Medicinal Chemistry (2017)

Experts (# of related papers)

View all Related Experts

Hossein Ghadiri Harvani (5)

Sharmin Kharrazi (3)

Other Related Docs

4. Nanovehicles for Co-Delivery of Anticancer Agents, Drug Discovery Today (2020)

5. Targeted Gold Nanoparticles Enable Molecular Ct Imaging of Head and Neck Cancer: An in Vivo Study, International Journal of Biochemistry and Cell Biology (2019)

6. Recent Advances and Trends in Nanoparticles Based Photothermal and Photodynamic Therapy, Photodiagnosis and Photodynamic Therapy (2022)

7. A Biocompatible Theranostic Nanoplatform Based on Magnetic Gadolinium-Chelated Polycyclodextrin: In Vitro and in Vivo Studies, Carbohydrate Polymers (2021)

8. Inhibitory Effect of Gold Nanoparticles Conjugated With Interferon Gamma and Methionine on Breast Cancer Cell Line, Asian Pacific Journal of Tropical Biomedicine (2016)

9. Gold Nanoparticle Conjugation and Tumor Accumulation of a Vegf Receptor-Targeting Peptidomimetic, Journal of the Iranian Chemical Society (2024)

10. Theranostic Muc-1 Aptamer Targeted Gold Coated Superparamagnetic Iron Oxide Nanoparticles for Magnetic Resonance Imaging and Photothermal Therapy of Colon Cancer, Colloids and Surfaces B: Biointerfaces (2016)

11. Transcriptional Regulation of the Colorectal Cancer Stem Cell Markers, Nanog and Oct4, Induced by a Thermodynamic-Based Therapy Approach, Iranian Journal of Public Health (2023)

12. Emerging Theranostic Silver and Gold Nanomaterials to Combat Prostate Cancer: A Systematic Review, Journal of Cluster Science (2019)

13. Gold Nanoparticle Parameters Play an Essential Role As Ct Imaging Contrast Agents, Journal of Nanostructures (2021)

14. Folate-Conjugated Gold Nanoparticle As a New Nanoplatform for Targeted Cancer Therapy, Journal of Cancer Research and Clinical Oncology (2016)

15. The Effect of Bismuth Nanoparticles in Kilovoltage and Megavoltage Radiation Therapy Using Magnetic Resonance Imaging Polymer Gel Dosimetry, Radiation Physics and Chemistry (2020)

16. Cancer Nanomedicine: Special Focus on Cancer Immunotherapy, Cancer Immunology: Bench to Bedside Immunotherapy of Cancers# Second Edition (2020)

17. Folic Acid-Cysteamine Modified Gold Nanoparticle As a Nanoprobe for Targeted Computed Tomography Imaging of Cancer Cells, Materials Science and Engineering C (2018)

18. Recent Advances in Gene Therapy-Based Cancer Monotherapy and Synergistic Bimodal Therapy Using Upconversion Nanoparticles: Structural and Biological Aspects, Biomedicine and Pharmacotherapy (2022)

19. Observation of Targeted Gold Nanoparticles in Nasopharyngeal Tumour Nude Mice Model Through Dual-Energy Computed Tomography, IET Nanobiotechnology (2021)

20. Gold Nanoparticles for Biomedical Imaging and Their Biological Response, New Developments in Gold Nanomaterials Research (2016)

Style	Citing Format
MLA	Banstola A, et al.. "Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer." Macromolecular Research, vol. 26, no. 11, 2018, pp. 955-964.
APA	Banstola A, Emami F, Jeong JH, Yook S (2018). Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer. Macromolecular Research, 26(11), 955-964.
Chicago	Banstola A, Emami F, Jeong JH, Yook S. "Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer." Macromolecular Research 26, no. 11 (2018): 955-964.
Harvard	Banstola A et al. (2018) 'Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer', Macromolecular Research, 26(11), pp. 955-964.
Vancouver	Banstola A, Emami F, Jeong JH, Yook S. Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer. Macromolecular Research. 2018;26(11):955-964.
BibTex	@article{ author = {Banstola A and Emami F and Jeong JH and Yook S}, title = {Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer}, journal = {Macromolecular Research}, volume = {26}, number = {11}, pages = {955-964}, year = {2018} }
RIS	TY - JOUR AU - Banstola A AU - Emami F AU - Jeong JH AU - Yook S TI - Current Applications of Gold Nanoparticles for Medical Imaging and As Treatment Agents for Managing Pancreatic Cancer JO - Macromolecular Research VL - 26 IS - 11 SP - 955 EP - 964 PY - 2018 ER -

Science Communicator Platform

Authors

Abstract