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The Promising Potentials of Capped Gold Nanoparticles for Drug Delivery Systems Publisher Pubmed



Khoshnevisan K1, 2 ; Daneshpour M3 ; Barkhi M4 ; Gholami M2, 5 ; Samadian H6 ; Maleki H6
Authors
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Authors Affiliations
  1. 1. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. University of Applied Science and Technology (UAST), Zar Center, Karaj, Iran
  5. 5. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Drug Targeting Published:2018


Abstract

Fabrication and characterisation of gold nanoparticles (GNPs) through reducing agents and different capped agents are one of their most attractive applications in biomedicine. GNPs are coated using various agents such as carbohydrate, amino acids, peptides and proteins. These capped gold nanoparticles (C-GNPs) are applied for wide different applications including drug delivery in the recent decade and potential treatment and diagnosis in drug delivery systems (DDS). Recent studies have shown that these novel compounds and conjugated-nanoparticles drugs play a key role for the promising cure of high-risk refractory diseases. In addition, it seems that these compounds have a capability for potential treatment of certain cancers. In this review, a well-defined description of C-GNPs and the application of these nanoparticles are discussed. Our study revealed that C-GNPs with anticancer drugs or new compounds could be potentially applied for biomedical usage especially in cancer therapy. © 2017 Informa UK Limited, trading as Taylor & Francis Group.
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