Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives

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Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives Publisher

Esmati N¹ ; Foroughian M¹ ; Saeedi M² ; Mahdavi M² ; Khoshneviszadeh M^{2, 3} ; Firuzi O³ ; Tanideh N³ ; Miri R³ ; Edraki N^{2, 3} ; Shafiee A² ; Foroumadi A^{1, 2}

Source: Journal of Heterocyclic Chemistry Published:2015

Abstract

Three-component reaction of 4-hydroxy-2H-benzo[h]chromen-2-one, aromatic aldehydes, and malononitrile in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in ethanol at room temperature affords good yields of novel dihyrobenzo[h]pyrano[3,2-c]chromene derivatives. The synthesized compounds examined by MTT assays for cytotoxic activity in two human cancer cell lines (MOLT-4, HL-60). Most of the evaluated compounds showed low inhibitory activity against tumor cell line at micromolar concentrations. © 2014 HeteroCorporation.

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Style	Citing Format
MLA	Esmati N, et al.. "Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives." Journal of Heterocyclic Chemistry, vol. 52, no. 1, 2015, pp. 97-104.
APA	Esmati N, Foroughian M, Saeedi M, Mahdavi M, Khoshneviszadeh M, Firuzi O, Tanideh N, Miri R, Edraki N, Shafiee A, Foroumadi A (2015). Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives. Journal of Heterocyclic Chemistry, 52(1), 97-104.
Chicago	Esmati N, Foroughian M, Saeedi M, Mahdavi M, Khoshneviszadeh M, Firuzi O, Tanideh N, et al.. "Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives." Journal of Heterocyclic Chemistry 52, no. 1 (2015): 97-104.
Harvard	Esmati N et al. (2015) 'Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives', Journal of Heterocyclic Chemistry, 52(1), pp. 97-104.
Vancouver	Esmati N, Foroughian M, Saeedi M, Mahdavi M, Khoshneviszadeh M, Firuzi O, et al.. Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives. Journal of Heterocyclic Chemistry. 2015;52(1):97-104.
BibTex	@article{ author = {Esmati N and Foroughian M and Saeedi M and Mahdavi M and Khoshneviszadeh M and Firuzi O and Tanideh N and Miri R and Edraki N and Shafiee A and Foroumadi A}, title = {Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives}, journal = {Journal of Heterocyclic Chemistry}, volume = {52}, number = {1}, pages = {97-104}, year = {2015} }
RIS	TY - JOUR AU - Esmati N AU - Foroughian M AU - Saeedi M AU - Mahdavi M AU - Khoshneviszadeh M AU - Firuzi O AU - Tanideh N AU - Miri R AU - Edraki N AU - Shafiee A AU - Foroumadi A TI - Synthesis and Cytotoxic Activity of Some Novel Dihyrobenzo[H]Pyrano [3,2-C]Chromene Derivatives JO - Journal of Heterocyclic Chemistry VL - 52 IS - 1 SP - 97 EP - 104 PY - 2015 ER -

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