Host Factors: Implications in Immunopathogenesis of Covid-19

Host Factors: Implications in Immunopathogenesis of Covid-19 Publisher Pubmed

Jafarpour R¹ ; Pashangzadeh S^{2, 3} ; Dowran R^{4, 5}

Source: Pathology Research and Practice Published:2021

Abstract

Coronavirus disease 2019 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is more serious in people with underlying diseases, but the cause of healthy people with progressive disease is largely unknown. Host genetic factors such as ACE2 variants, IFITM-3, HLA, TMRSS2, and furin polymorphisms appear to be one of the agents involved in the progression of the COVID-19 and outcome of the disease. This review discusses the general characteristics of SARS-CoV-2, including viral features, receptors, cell entry, clinical findings, and the main human genetic factors that may contribute to the pathogenesis of COVID-19 and get the patients’ situation more complex. Further knowledge in this context may help to find a way to prevent and treat this viral pneumonia. © 2021 Elsevier GmbH

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Nima Rezaei (3)

Farshid Noorbakhsh (1)

Style	Citing Format
MLA	Jafarpour R, Pashangzadeh S, Dowran R. "Host Factors: Implications in Immunopathogenesis of Covid-19." Pathology Research and Practice, vol. 228, no. , 2021, pp. -.
APA	Jafarpour R, Pashangzadeh S, Dowran R (2021). Host Factors: Implications in Immunopathogenesis of Covid-19. Pathology Research and Practice, 228(), -.
Chicago	Jafarpour R, Pashangzadeh S, Dowran R. "Host Factors: Implications in Immunopathogenesis of Covid-19." Pathology Research and Practice 228, no. (2021): -.
Harvard	Jafarpour R, Pashangzadeh S, Dowran R (2021) 'Host Factors: Implications in Immunopathogenesis of Covid-19', Pathology Research and Practice, 228(), pp. -.
Vancouver	Jafarpour R, Pashangzadeh S, Dowran R. Host Factors: Implications in Immunopathogenesis of Covid-19. Pathology Research and Practice. 2021;228():-.
BibTex	@article{ author = {Jafarpour R and Pashangzadeh S and Dowran R}, title = {Host Factors: Implications in Immunopathogenesis of Covid-19}, journal = {Pathology Research and Practice}, volume = {228}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Jafarpour R AU - Pashangzadeh S AU - Dowran R TI - Host Factors: Implications in Immunopathogenesis of Covid-19 JO - Pathology Research and Practice VL - 228 IS - SP - EP - PY - 2021 ER -

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