Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks

Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks Publisher Pubmed

Sadoughi F¹ ; Hallajzadeh J² ; Asemi Z¹ ; Mansournia MA³ ; Alemi F⁴ ; Yousefi B^{4, 5}

Show Affiliations

1. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran
2. Department of Biochemistry and Nutrition, Research Center for Evidence-Based Health Management, Maragheh University of Medical Sciences, Maragheh, Iran
3. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
4. Department of Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
5. Molecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Source: DNA Repair Published:2021

Abstract

Our genome bears tens of thousands of harms and devastations per day; In this regard, numerous sophisticated and complicated mechanisms are embedded by our cells in furtherance of remitting an unchanged and stable genome to their next generation. These mechanisms, that are collectively called DDR, have the duty of detecting the lesions and repairing them. it's necessary for the viability of any living cell that sustain the integrity and stability of its genetic content and this highlights the role of mediators that transduce the signals of DNA damage to the cell cycle in order to prevent the replication of a defective DNA. In this paper, we review the signaling pathways that lie between these processes and define how different ingredients of DDR are also able to affect the checkpoint signaling. © 2021 Elsevier B.V.

Related Docs

View other Related Docs

1. The Role of Dna Damage Response in Chemo- and Radio-Resistance of Cancer Cells: Can Ddr Inhibitors Sole the Problem?, DNA Repair (2021)

2. Negative Feedback Loop in the Activation of Non-Homologous End Joining Dna Repair Pathway in Helicobacter Pylori Infected Patients With Gastritis, Scientific Reports (2024)

3. Ataxia Telangiectasia Syndrome: Moonlighting Atm, Expert Review of Clinical Immunology (2017)

4. Beta-Glucans Is a Potential Inhibitor of Ovarian Cancer: Based on Molecular and Biological Aspects, Current Pharmaceutical Biotechnology (2022)

5. Melatonin: A Smart Molecule in the Dna Repair System, Cell Biochemistry and Function (2022)

6. The Horizon of Gene Therapy in Modern Medicine: Advances and Challenges, Advances in Experimental Medicine and Biology (2020)

7. Association of Polymorphisms in Nucleotide Excision Repair Pathway Genes With Susceptibility to Cutaneous Melanoma; [Vztah Mezi Polymorfizmy Genu Nukleotidove Excizni Reparace a Nachylnosti Ke Koznimu Melanomu], Klinicka Onkologie (2021)

8. An Evidence-Based Review of the Genotoxic and Reproductive Effects of Sulfur Mustard, Archives of Toxicology (2017)

Experts (# of related papers)

View all Related Experts

Mohammad Ali Mansournia (2)

Mohammad Abdollahi (2)

Style	Citing Format
MLA	Sadoughi F, et al.. "Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks." DNA Repair, vol. 98, no. , 2021, pp. -.
APA	Sadoughi F, Hallajzadeh J, Asemi Z, Mansournia MA, Alemi F, Yousefi B (2021). Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks. DNA Repair, 98(), -.
Chicago	Sadoughi F, Hallajzadeh J, Asemi Z, Mansournia MA, Alemi F, Yousefi B. "Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks." DNA Repair 98, no. (2021): -.
Harvard	Sadoughi F et al. (2021) 'Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks', DNA Repair, 98(), pp. -.
Vancouver	Sadoughi F, Hallajzadeh J, Asemi Z, Mansournia MA, Alemi F, Yousefi B. Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks. DNA Repair. 2021;98():-.
BibTex	@article{ author = {Sadoughi F and Hallajzadeh J and Asemi Z and Mansournia MA and Alemi F and Yousefi B}, title = {Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks}, journal = {DNA Repair}, volume = {98}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Sadoughi F AU - Hallajzadeh J AU - Asemi Z AU - Mansournia MA AU - Alemi F AU - Yousefi B TI - Signaling Pathways Involved in Cell Cycle Arrest During the Dna Breaks JO - DNA Repair VL - 98 IS - SP - EP - PY - 2021 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract