Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Biofilm-Associated Bacterial Infections Unrelated to Indwelling Devices Publisher Pubmed



Mirzaei R1 ; Mohammadzadeh R2 ; Alikhani MY1 ; Shokri Moghadam M3 ; Karampoor S4 ; Kazemi S1 ; Barfipoursalar A5 ; Yousefimashouf R1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
  2. 2. Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Microbiology, School of Health, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Microbiology, Shahid Rahimi Hospital, Khorramabad, Iran

Source: IUBMB Life Published:2020


Abstract

Biofilms are microbial communities established in the self-produced extracellular substances that include up to 80% of associated microbial infections. During biofilm formation, bacterial cells shift from the planktonic forms to aggregated forms surrounded by an extracellular polymeric substance. The bacterial biofilm shows resistance against immune reactions as well as antibiotics and is potentially able to cause disorders by both device-related and nondevice-related infections. The nondevice-related bacterial biofilm infections include dental plaque, urinary tract infections, cystic fibrosis, otitis media, infective endocarditis, tonsillitis, periodontitis, necrotizing fasciitis, osteomyelitis, infectious kidney stones, and chronic inflammatory diseases. In this review, we will summarize and examine the literature about bacterial biofilm infections unrelated to indwelling devices. © 2020 International Union of Biochemistry and Molecular Biology